SHARC™ HPLC columns is the latest, innovative column from SIELC Technologies, the inventors of Primesep®.
SHARC™ columns are the first commercially available columns with separation based primarily on hydrogen bonding.

Primesep stationary phases offer unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. A wide range of HPLC columns with id's from 0.5 mm to 22 mm is available. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service is available for customers. Ask about special custom LC-phases tailored for specific separations.

Two complimentary columns, Obelisc R and Obelisc N, based on Liquid Separation Cell ( LiSC ™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures.

Promix is an alternative chromatography technology for efficient resolution of peptides and proteins. The technology is based on a combination of two interactions - hydrophobic and ionic. This approach is possible due to a new type of separation media: a chemical combination of hydrophobic and ionic functional groups on a ligand bonded to a silica support. With this phase, unparalleled selectivity and peak capacity can be achieved. Independent adjustment of the amount of buffer and organic modifier creates an infinite number of separation conditions that are suitable for many types of biomolecules.

SIELC has developed the Legacy column, which can be used in many USP Validated methods. SIELC is developing L1, L3, L7, L8, L10, L11, L14, L16, L26, L28, and L44 columns.

• SIELC Technologies is offering a patented design of capillary, analytical, and preparative hardware for HPLC.
• Unified cylindrical shape of the columns is a signature hardware style developed and produced by SIELC.
• Superior performance, distinguished look, and reduced hardware costs are just a few benefits of the new design.

SIELC offers a new design of fittings for HPLC. It combines reduced costs, with attractive appearance and premium performance. Two versions of fitting available for high pressure applications up to 5000 psi (350 bar) and ultrahigh pressure applications 14000 psi (1000 bar).
Some benefits of SIELC fittings: finger-tight installation, break-resistant, fully metal thread, improves heat transfer, one-size-fits-most applications, several color options.

Different devices often used in chromatography applications to build special capabilities of the instrumentation. SIELC Technologies is offering several innovative devices:

• High pressure switching valve
• Low pressure reciprocating pump
• Flow splitter
• Dynamic mixer
• Chromatography data acquisition software and A/D USB converter

Multipacking device for self-packing of preparative columns using only preparative pump.

• No additional equipment required if you have prep LC system
• One hardware set provide columns of different length
• Dynamic and static bed compression
• Optional air or water heating/cooling