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New Products
New advanced ultra high pressure fittings from SIELC
Recently Developed Methods
HPLC Analysis of 5-Fluorouracil on Primesep Columns with LC/MS Compatible Mobile Phase
HPLC Separation of Citric Acid and Phosphate Ions in HILIC Chromatography
HILIC Separation of Common Preservatives - Citric Acid, Ascorbic Acid and EDTA
HPLC Derivatization and Quantitative Analysis of Glycerol
HPLC Separation of Components of Excedrin
HPLC Analysis of Motrin Cough & Cold Composition
HPLC Separation of Amino Acids in Supplements Composition in Mixed-Mode
HPLC Analysis of Alginic Acid in Heartburn Tablets
Other Methods
New capillary and preparative column hardware
New Specialty Columns from SIELC
New comprehensive guide for HPLC Method Development
SIELC Technologies offers a free and fully confidential method development service to assist you in your column selection and to save you time and money. Samples are screened on up to 6 different phases.
- Analysis by SIELC's team of experienced chromatographers
- Fast turn around
- Full method details provided
- LC/MS/ELSD compatible
- Method scalable to preparative chromatography
SIELC Technologies introduces a new HPLC method development tool.
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Obelisc
Two complimentary columns, Obelisc R and Obelisc N, based on Liquid Separation Cell ( LiSC ™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures.
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Promix
Promix is an alternative chromatography technology for efficient resolution of peptides and proteins. The technology is based on a combination of two interactions - hydrophobic and ionic. This approach is possible due to a new type of separation media: a chemical combination of hydrophobic and ionic functional groups on a ligand bonded to a silica support. With this phase, unparalleled selectivity and peak capacity can be achieved. Independent adjustment of the amount of buffer and organic modifier creates an infinite number of separation conditions that are suitable for many types of biomolecules. |
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HPLC Hardware
- SIELC Technologies is offering a patented design of capillary, analytical, and preparative hardware for HPLC.
- Unified cylindrical shape of the columns is a signature hardware style developed and produced by SIELC.
- Superior performance, distinguished look, and reduced hardware costs are just a few benefits of the new design.
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Phlex LDS
This flexible liquid delivery system offers a new approach for adding HPLC buffers and other liquids.
- Eliminate premixing of buffered mobile phases
- Add modifiers such as TEA and formic acid to an SFC system
- Use as a high-pressure injector in preparative separation chromatography
- Eliminate contamination of HPLC pumps and degassers with buffer components
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Fittings
SIELC offers a new design of fittings for HPLC. It combines reduced costs, with attractive appearance and premium performance. Two versions of fitting available for high pressure applications up to 5000 psi (350 bar) and ultrahigh pressure applications 14000 psi (1000 bar).
Some benefits of SIELC fittings: finger-tight installation, break-resistant, fully metal thread, improves heat transfer, one-size-fits-most applications, several color options. |
Recent Publications
The Do's and Don'ts of Method Development in Mixed-Mode Chromatography
Part 1
HPLC Columns for Simultaneous Analysis of Counter-Ions
Pharmaceutical Analysis: What Is Your Problem?
Acetonitrile Shortage - Is It Time to Put Your HILIC Columns Away?
Competing in HPLC Olympics - Comparison of Modern LC Columns
Systematic Approach to Chromatography of Quaternary Amines
New Mixed-Mode HILIC - Advances in Retention Control and Selectivity
New Mixed-Mode Approach - Taking Control Of Your Separations
Universal HPLC Column: Old Myth or Modern Reality?
Primesep SB: A New Tool for Separation of Small Molecules
Is There a Mystery in HPLC Separations?
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