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SHARC™ HPLC columns is the latest, innovative column from SIELC Technologies, the inventors of Primesep®. SHARC™ columns are the first commercially available columns with separation based primarily on hydrogen bonding.
SHARC stands for Specific Hydrogen-bond Adsorption Resolution Column.
Hydrogen bonding is an interaction (attraction) of bound hydrogen atom to the molecules with electronegative atoms such as oxygen, nitrogen, fluorine.
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Two complimentary columns, Obelisc R and Obelisc N, based on Liquid Separation Cell ( LiSC ™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures. |
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SIELC has developed the Legacy column, which can be used in many USP Validated methods. SIELC is developing L1, L3, L7, L8, L10, L11, L14, L16, L26, L28, and L44 columns. |
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- SIELC Technologies is offering a patented design of capillary, analytical, and preparative hardware for HPLC.
- Unified cylindrical shape of the columns is a signature hardware style developed and produced by SIELC.
- Superior performance, distinguished look, and reduced hardware costs are just a few benefits of the new design.
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SIELC offers a new design of fittings for HPLC. It combines reduced costs, with attractive appearance and premium performance. Two versions of fitting available for high pressure applications up to 5000 psi (350 bar) and ultrahigh pressure applications 14000 psi (1000 bar). Some benefits of SIELC fittings: finger-tight installation, break-resistant, fully metal thread, improves heat transfer, one-size-fits-most applications, several color options. |
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Different devices often used in chromatography applications to build special capabilities of the instrumentation. SIELC Technologies is offering several innovative devices:
- High pressure switching valve
- Low pressure reciprocating pump
- Flow splitter
- Dynamic mixer
- Chromatography data acquisition software and A/D USB converter
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Multipacking device for self-packing of preparative columns using only preparative pump.
- No additional equipment required if you have prep LC system
- One hardware set provide columns of different length
- Dynamic and static bed compression
- Optional air or water heating/cooling
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New advanced ultra high pressure fittings from SIELC

New advanced dynamic mixers from SIELC

Guards columns

HPLC Separation of Nucleosides and Deoxynucleosides
USP Methods for the Analysis of Procainamide
USP Methods for the Separation of Propranolol and Procainamide Using the Legacy L1 Column
USP Methods for the Analysis of Norepinephrine using the Legacy L1 Column
HPLC Separation of Inosine and Deoxyinosine
HPLC Separation of Succinylcholine and Choline Using a Primesep 200 Column
HPLC Separation of the Nonionic Surfacant Triton-X-100
HPLC Analysis of Azide Ion on Obelisc N Column
HPLC Analysis of Bendamustine and Related Impurities
HPLC Analysis of Calcium Ions in Maple Syrup

New Specialty Columns from SIELC
New comprehensive guide for HPLC Method Development
SIELC Technologies offers a free and fully confidential method development service
to assist you in your column selection and to save you time and money. Samples are screened on up to 6 different phases.
- Analysis by SIELC's team of experienced chromatographers
- Fast turn around
- Full method details provided
- LC/MS/ELSD compatible
- Method scalable to preparative chromatography
SIELC Technologies introduces a new HPLC method development tool.
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