Tramadol

Tramadol structural formula

UV Spectra of Tramadol

UV Spectra of Tramadol

CAS Number27203-92-5
Molecular FormulaC16H25NO2
Molecular Weight263.382
InChI KeyTVYLLZQTGLZFBW-ZBFHGGJFSA-N
LogP2.44
Synonyms
  • Tramadol
  • 27203-92-5
  • Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-rel-
  • Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, cis-(+/-)-
  • Cyclohexanol, 2-[(dimethylamino)methyl]-1-(m-methoxyphenyl)-
  • (+/-)-Tramadol
  • Biomadol
  • CG 315E
  • cis-Tramadol
  • E 265
  • Labesfal
  • Racemic tramadol
  • Ryzolt
  • Tiparol
  • Tradolan
  • Tramadis
  • Tramadol Contramid
  • Tramadon
  • Tramaliv
  • Trapidol
  • U 26255A
  • Zytram
  • Cyclohexanol, 2-((dimethylamino)methyl)-1-(m-methoxyphenyl)-
  • EINECS 248-319-6
  • Ralivia ER
  • Ralivia flashtab
  • Tramadolum
  • UNII-39J1LGJ30J
  • Tradonal odis
  • 73806-46-9
  • 113683-92-4

Applications:

HPLC Determination of Tramadol in Human Plasma and Urine Samples with FlipLC system

May 2, 2019


FlipLC™ is an alternative method to avoid the interference of most of the contaminants by the use of an isolation column and a high pressure switching valve before the separation column. This method allows sample cleaning and analyte separation in one automated process. The isolation column and the separation column should have orthogonal retention characteristics to operate efficiently in this setup. Mixed-mode columns with reverse phase and ion-exchange characteristics were used in this analysis.

Application Column

Primesep SB

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
Tramadol
Tramadol hydrochloride
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of Tramadol in Tablets on Primesep 200 Column

November 27, 2018

HPLC Determination of Tramadol in Tablets


HPLC Determination of Tramadol in Tablets_1153

 

Condition

Column Primesep 200, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 30/70%
Buffer H3PO4 – 0.1%
Flow Rate 1.0 ml/min
Detection UV, 216 nm

 

Description

Class of Compounds
Drug, Narcotic, Zwitterionic, Hydrophobic, Ionizable
Analyzing Compounds Tramadol

 

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Tramadol
Tramadol hydrochloride
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Tramadol

May 3, 2016

Chr_1050




Tramadol is a narcotic analgesic used to manage severe pain. It is a synthetic codeine analogue. The way it works is similar to opioids, such as morphine and codeine due to it acting on specific opioid receptors. An overdose on the drug can cause acute liver failure.Tramadol, also known as Ultram and other brand names, is a synthetic opiate used to treat moderate to severe pain. The painkilling effects of Tramadol last for about 6 hours. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Tramadol. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Tramadol

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.