Applications  →  HILIC Separation of Carboxylic Acids

HPLC Application of HILIC Separation of Carboxylic Acids



Hydrophilic acids are separated on Obelisc N mixed-mode HILIC column. Seven carboxylic acids are separated based on their polarity and pKa values. Changes in ionization states of acids and stationary phase can be used to control elution order of organic and inorganic acids.

Application Analytes:

Hydroxybenzoic Acid
Succinic Acid
Mandelic Acid
Methylmalonic Acid
Malic Acid
Fumaric Acid
Tartaric Acid

Application Detection:

ELSD/MS Detection
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