Applications  →  HPLC Separation of Drugs in Tylenol Cold and Cough Remedies

HPLC Application of HPLC Separation of Drugs in Tylenol Cold and Cough Remedies



Components of Tylenol Cold and Cough Remedy are separated on Obelisc R mixed-mode column. Method can be used to determine compounds in various cough and cold compositions. Neutral (acetaminophen), basic (chlorpheniramine, dextromethorphan and pseudoephedrine) and acidic (maleic acid/Maleate) components are analyzed with perfect peak shape and retention control. Method can be used in production, QC/QA and biological studies for quantitation of various components in pharmaceutical formulations (Advil, Tylenol, Dimetapp, Robitussin, NyQuil, etc)

Application Analytes:

Acetaminophen (Paracetamol)
Pseudoephedrine (PSE)
Dextromethorphan
Chlorpheniramine
Maleate

Application Detection:

UV Detection
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