Applications  →  Separation of Alginic Acid and Related Products

HPLC Application of Separation of Alginic Acid and Related Products



Alginate is used in various pharmaceutical preparations. Chemically, it is a linear copolymer with homopolymeric blocks of (1-4)-linked ?-D-mannuronate (M) and its C-5 epimer ?-L-guluronate (G) residues, respectively, covalently linked together in different sequences or blocks. Alginic acid can be separated from benzoate, citric acid and saccharin by mixed-mode chromatography on Primesep C HPLC column. This method can be used to quantitate alginic acid, citric acid or saccharin in complex mixtures. Various detection technique can be used (UV, ELSD, LC/MS), based on mobile phase selection.

Application Analytes:

Alginic Acid
Citric Acid
Benzoic Acid
Saccharin

Application Detection:

UV Detection
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