Separation of Diacid: Ion Exclusion mode



Primesep 100 separates a mixture of dicarboxylic acids in ion-exclusion mode with a mobile phase of water, acetonitrile (MeCN, ACN), and sulfuric acid (H2SO4) with UV detection at 210 nm. Baseline resolution of fumaric, maleic, malic, and succinic acids is obtained in less than 8 minutes. The separation combines ion-exclusion and reversed-phase mechanisms in one method.



Application Analytes:

Dicarboxylic Acids
Fumaric Acid
Maleic Acid
Malic Acid
Succinic Acid