5-Fluorouracil (5-FU, F5U)

5-Fluorouracil (5-FU, F5U) structural formula

CAS Number 51-21-8
Molecular Formula C4H3FN2O2
Molecular Weight 130.079 g/mol
InChI Key GHASVSINZRGABV-UHFFFAOYSA-N
LogP -0.890
Synonyms
  • 5-Fluorouracil
  • 5-Fluoropyrimidine-2,4(1H,3H)-dione
  • 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
  • 51-21-8
  • 5-FU
  • Fluorouracil, 5-
  • 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
  • 2,4-Dihydroxy-5-fluoropyrimidine
  • 2,4-Dioxo-5-fluoropyrimidine
  • 5-Fluoracyl
  • 5-Fluoro-2,4(1H,3H)-pyrimidinedione
  • 5-Fluoro-2,4-pyrimidinedione
  • 5-Fluoropyrimidine-2,4-diol
  • 5-FLUORURACIL
  • Adrucil
  • Carzonal
  • Fluoroblastin
  • Fluoroplex
  • fluorouracil
  • Fluorouracile
  • fluorouracilo
  • Fluoruracil
  • Flurablastin
  • Fluracedyl
  • Fluracil
  • Fluracilum
  • Ftoruracil
  • Kecimeton
  • NSC 19893
  • Phthoruracil
  • Phtoruracil
  • Queroplex
  • Timazin
  • URACIL, 5-FLUORO-
  • Cinco FU
  • EINECS 200-085-6
  • 5-Fluoropyrimidin-2,4-diol
  • 5-Fluoropyrimidine-2,4-dione
  • Fluoro-uracile
  • Fluoro-uracilo
  • Fluorouracilum
  • Fluro uracil
  • Fluroblastin
  • NSC-19893
  • 5-Fluor-2,4(1H,3H)-pyrimidindion
  • 5-Fluor-2,4-dihydroxypyrimidin
  • 5-Fluor-2,4-pyrimidindiol
  • 5-Fluoracil
  • UNII-U3P01618RT
  • Fluorouracil Cream
  • 1004-03-1
  • 4921-97-5
  • 79108-01-3

Applications:


HPLC Analysis of 5-Fluorouracil on Primesep Columns with LC/MS Compatible Mobile Phase



5-Fluorouracil (5-FU) is pyrimidine analog which is used as anti-cancer drug. 5-Fluorouracil is very polar non-ionizable compound which is hard to retain by reversed-phase chromatography. Ion-pairing reagent cannot be employed due to non-ionizable nature of the compound. 5-fluorouracil is retained in zero organic on Primesep 100 and Primesep P columns. Both columns demonstrate perfect peak shape. 5-FU can be monitored by UV, or by ELSD, LC/MS or Corona CAD.



Application Analytes:

5-Fluorouracil (5-FU, F5U)