alpha-Aminobutyric Acid

CAS Number 2835-81-6
Molecular Formula 08902
Molecular Weight 103.121 g/mol
InChI Key QWCKQJZIFLGMSD-UHFFFAOYSA-N
LogP -2.5
Synonyms
  • DL-2-Aminobutyric acid
  • 2-Aminobutyric acid
  • 2-Aminobutanoic acid
  • 2835-81-6
  • Butanoic acid, 2-amino-
  • ALPHA-AMINOBUTYRIC ACID
  • Butyrine
  • DL-2-Amino-n-butyric acid
  • AABA
  • DL-alpha-Amino-n-butyric acid
  • H-DL-ABU-OH
  • alpha-Amino-n-butyric acid
  • 2-amino-butyric acid
  • Butanoic acid, amino-
  • DL-2-Aminobutanoic acid
  • 2-AMINO-N-BUTYRIC ACID
  • L-.alpha.-Aminobutyrate
  • Butyric acid, 2-amino-
  • l(+)-2-aminobutyric acid
  • 80-60-4
  • ABU
  • L-.alpha.-Aminobutyric acid
  • DL-.alpha.-Aminobutyric acid
  • Butyric acid, 2-amino-, L-
  • Homoalanine
  • CHEBI:35621
  • L-.alpha.-Amino-n-butyric acid
  • DL-.alpha.-Amino-n-butyric acid
  • NSC3251
  • QWCKQJZIFLGMSD-UHFFFAOYSA-N
  • Butanoic acid, 2-amino-, (S)-
  • MFCD00008093
  • DL-.alpha.-Amino-n-butyric acid (.beta.-form)
  • H-DL-2-ABU-OH
  • Ethylglycine
  • Butyric acid, 2-amino-, DL-
  • NSC 3251
  • EINECS 201-296-6
  • EINECS 220-616-5
  • AMINOBUTYRIC ACID,-2-, ALPHA
  • Butanoic acid, 2-amino-, (.+-.)-
  • DL-2-Aminobutyricacid
  • HOMO-DL-ALANINE
  • l-2-aminobutanoic acid
  • 2-aminobutyric acid, dl
  • 3-amino-3-carboxypropyl
  • AI3-15284
  • DL-alpha-Amino-n-butyric acid (beta-form)
  • AC1Q2SIK
  • ACMC-209gq6

Applications:


HPLC Separation of Isomers of Aminobutyric Acids



Primesep C separates the isomers of aminobutyric acids by a combination of reversed-phase and ionic interaction mechanisms. alpha-Aminobutyric acid, beta-Aminobutryic acid, and gamma-Aminobutyric acid (GABA) are baseline resolved without ion-pair reagents. The HPLC separation uses a mobile phase of water, acetonitrile (MeCN, ACN) ammonium acetate with evaporative light scattering detection (ELSD).



Application Analytes:

Aminobutyric Acids
alpha-Aminobutyric Acid
beta-Aminobutyric Acid
gamma-Aminobutyric Acid (GABA)

HPLC Separation of alpha-Aminobutyric, beta-Aminobutyric, and gamma-Aminobutyric acids on Obelisc N


GABA (neurotransmitter) and its isomers are polar zwitter-ionic compounds. Due to the position of amino-groups, all three compounds show different polar and basic properties. The isomers of aminobuturic acid are separated on an Obelisc N HILIC/cation-exchange column. Buffer concentration has a different effect on retention of alpha-, beta-, and gamma-aminobutyric acid. This general and robust method can be used for separation of other polar and ionizable compounds and isomers by mixed-mode chromatography.



Application Analytes:

Zwitterion
alpha-Aminobutyric Acid
beta-Aminobutyric Acid
gamma-Aminobutyric Acid (GABA)