| CAS Number | 31121-93-4 |
|---|---|
| Molecular Formula | C13H17NaO2 |
| Molecular Weight | 228.267 |
| InChI Key | PTTPUWGBPLLBKW-UHFFFAOYSA-M |
| LogP | 2.98 |
| Synonyms |
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Applications:
USP Methods for the Analysis of Ibuprofen using a Legacy L1 Column
February 20, 2019
| Column | Legacy L1, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 45/55% |
| Buffer | H3PO4 – 0.01 M |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 230 nm |
| Class of Compounds |
Drug, Acid, Hydrophilic, Ionizable, Neutral, Hydrophobic |
| Analyzing Compounds | Ibuprofen, Benzophenone |
Application Column
Legacy L1
SIELC's family of Legacy columns is based on the United States Pharmacopeia's (USP) published chromatographic methods and procedures. Numerous brands have columns used in USP reference standards and methods. USP has created various designations to group together columns with similar types of packing and properties in the solid phase. SIELC's Legacy columns adhere to these strict requirements and properties, allowing you to easily replace older columns that are no longer available without needing to significantly modify your method or SOPs.
Select optionsIbuprofen Sodium
HPLC Separation of Acidic Drugs and Counter-Ions on Obelisc R Column
October 4, 2010
Mixed-mode columns allow to quantitate drugs and their counter-ions in one run. Hydrophobic acidic drug and hydrophilic inorganic counter-ions are separated and quantified on an Obelisc R HPLC trimodal column. This column can be used to quantify hydrophilic basic and hydrophilic acidic drugs, hydrophobic basic and hydrophobic acidic drugs, and corresponding organic and inorganic counter-ions. Various detection techniques can be applied to obtain reliable and robust method. Mixed-mode chromatography allows to retain ionizable compounds without ion-pairing reagent. This HPLC method can be adopted as universal and robust approach for analysis basic and acidic drugs and their counter-ions. Method is compatible with various detection techniques – ELSD, UV, CAD, and LC/MS.
Application Column
Obelisc R
SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.
Select optionsIbuprofen Sodium
Naproxen Sodium
UV Detection
