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Separation of Methylmalonic Acid HPLC Separation of Organic Acids in HILIC Mode on Primesep N Column  Ascorbic, methylmalonic and succinic are weak organic acids. Retention of these three acids is achieved on Primesep N column in HILIC mode using acetonitrile/water and ammonium acetate. Compounds are monitored by ELSD. Method can be used for determination of ascorbic acid (Vitamin C), methylmalonic acid and succinic acid in various matrices. Other polar organic acids can be analyzed on this HILIC column. Application Analytes: Succinic Acid Ascorbic Acid Methylmalonic Acid Application Detection: ELSD/MS Detection HPLC Separation of Succinic and Methylmalonic Acids
Application Analytes: Methylmalonic Acid Succinic Acid Application Detection: ELSD/MS Detection HILIC Separation of Carboxylic Acids  Hydrophilic acids are separated on Obelisc N mixed-mode HILIC column. Seven carboxylic acids are separated based on their polarity and pKa values. Changes in ionization states of acids and stationary phase can be used to control elution order of organic and inorganic acids. Application Analytes: Hydroxybenzoic Acid Succinic Acid Mandelic Acid Methylmalonic Acid Malic Acid Fumaric Acid Tartaric Acid Application Detection: ELSD/MS Detection |
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