CAS Number | 13922-41-3 |
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Molecular Formula | C10H9BO2 |
Molecular Weight | 171.99 |
InChI Key | HUMMCEUVDBVXTQ-UHFFFAOYSA-N |
Synonyms |
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Applications:
HPLC Separation of Aromatic Boronic Acids
July 8, 2011
Boronic acid is alkyl, or aryl substituted, boric acid. Boronic acid can form complexes with sugars, amines, and amino acids. Four aromatic boronic acids were separated on a Primesep P mixed-mode reversed-phase cation-exchange column. Primesep P column also has an aromatic fragment which provides pi-pi interaction. Compounds can be monitored by UV, ELSD, CAD and LC/MS. Various mobile phases can be employed for HPLC analysis of boronic acids.
Column | Primesep P, 4.6×150 mm, 5 µm, 100A |
Mobile Phase | MeCN/H2O |
Buffer | H2SO4 |
Flow Rate | 1.0 ml/min |
Detection | UV 270 nm |
Class of Compounds |
Drug, Acid, Hydrophobic, Ionizable |
Analyzing Compounds | Chlorohenyl-4-boronic acid, Naphtalene-1-boronic acid, Biphenyl-4-boronic acid, 4-(1-naphthyl)phenylboronic acid |
Application Column
Primesep P
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options4-Chlorophenylboronic acid
Biphenyl-4-boronic acid
Naphthalene-1-boronic acid