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Method Development Guide - Hydrophobic

Step 2

We have established that your compound is hydrophobic. Now we need to know whether your analyte is ionizable or neutral. Please choose a button below to move to the next step.

Is your compound . or .?

 

Ionizable compounds have molecules which have at least one charged functional group in a solution within a pH range from 2 to 7. Under these conditions, basic compounds are positively charged and acidic compounds are negatively charged.

Neutral compounds have no charge in solution at a pH range from 1.5 to 7.0.
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