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Obelisc R HPLC Columns

Obelisc R is a reverse-phase analytical column and can be used in traditional, reversed-phase type applications.

  • Due to the presence of ionic groups and a long hydrophobic chain, Obelisc R offers additional retention and tuning that is not available with traditional reversed-phase columns.
  • Multiple separation modes (RP, NP, IE).
  • Mass spec, ELSD, preparative and low UV (<220 nm) compatible, low concentration buffers.


Obelisc R columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A


Obelisc R Application Examples


Comparison of Obelisc R to C18 columns for the Separation of Aminopyridine Isomers
Comparison of the Separation of Polar Drugs on Obelisc R and Zorbax SB-AQ
Effect of mobile phase composition on retention of 3 compounds on Obelisc R
HPLC Analysis of Active Drug in a Formulation
HPLC Analysis of Components of Ionic Liquids by Mixed-Mode Chromatography
HPLC Separation of Acidic Drugs and Counter-Ions on Obelisc R Column
HPLC Separation of Amino Acids on Obelisc R Column
HPLC Separation of Amino Acids, Bases, Acids, and Neutrals on Obelisc R
HPLC Separation of Aromatic Compounds (PAH) on Mixed-Mode and Reverse Phase Columns
HPLC Separation of Aspartic Acid and Asparagine on Obelisc R Column
HPLC Separation of Drugs in Advil Allergy and Sinus
HPLC Separation of Drugs in Tylenol Cold and Cough Remedies
HPLC Separation of Methyl Paraben, Benzonitrile, Propyl Paraben, and Toluene on Mixed-Mode and Reverse Phase Columns
HPLC Separation of Neurotransmitters and Related Drugs
HPLC Separation of Polar and Hydrophobic Drugs on Obelisc R and N
HPLC Separation of Prednisolone, Atrolactic Acid, and Ibuprofen on Mixed-Mode Column
HPLC Separation of Tylosin and Albendazole
HPLC Separation Paraquat and Diquat on Obelisc R
Retention of Amikacin on Obelisc R Column
Separation of Drugs in Mixed-Mode HPLC
Simultaneous Separation of Melamine and Cyanuric Acid

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