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Primesep P HPLC Columns

Primesep P is a reverse-phase analytical column with embedded aromatic and acidic ion-pairing groups.

  • Improves retention of basic compounds by cation-exchange mechanism.
  • Separates aromatic compounds by difference in pi-pi interaction.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.


Primesep P columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A


Primesep P Application Examples


Effect of Buffer and Chemistry of Column Stationary Phase on Resolution of Neutral Compounds
Effect of Buffer Concentration on Resolution of Neutral Compounds (Prednisolone and D-Glucose Pentaacetate)
HPLC Analysis of 5-Fluorouracil on Primesep Columns with LC/MS Compatible Mobile Phase
HPLC Separation of Bendazoles on Primesep P Column
HPLC Separation of Neurotransmitters

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