LiSC - Living Separation Cell

Similarities to a living cell

• The cell internal environment is very different from the external environment (mobile phase);
• The pore walls form the dimensions and structure of the liquid separation cell;
• The cell internal environment has stationary (bound) and exchangeable (mobile) components;
• The pH and ionic strength inside the cell differs from outside the cell;
• The pore opening acts as a membrane channel for the analytes;
• The cell responds to changes in external environment with physical and chemical changes
• These changes include conformational changes in the long hydrophobic and hydrophilic chains, degree of ionization, charge distribution and counter-ion properties.