4-Acetylbenzoic Acid

4-Acetylbenzoic Acid

CAS Number586-89-0
Molecular FormulaC9H8O3
Molecular Weight164.16
InChI KeyQBHDSQZASIBAAI-UHFFFAOYSA-N
LogP1.6
Synonyms
  • 4-ACETYLBENZOIC ACID
  • 586-89-0
  • Benzoic acid, 4-acetyl-
  • 4-Acetyl-benzoic acid
  • p-acetylbenzoic acid
  • 4'-Acetophenonecarboxylic Acid
  • QBHDSQZASIBAAI-UHFFFAOYSA-N
  • MFCD00002561
  • SBB051425
  • 4-Acetylbenzoicacid

Applications:

Uv-Vis Spectrum of 4-Acetylbenzoic Acid

February 13, 2026
Access the UV-Vis Spectrum SIELC Library

If you are looking for optimized HPLC method to analyze 4-Acetylbenzoic Acid check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

 

 

 

 

 

 

 

Application Analytes:
4-Acetylbenzoic Acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Benzoic and Acetylbenzoic acid in Hydrogen-Bonding Mode

May 11, 2015

A general approach for analysis of various organic acids with MS detection in negative mode was developed using hydrogen-bonding stationary phase – SHARC 1. A highly sensitive method allows to analyze traces of organic acids in various matrices using ACN/MeOH/ammonia mobile phase. In hydrogen-bonding chromatography acetonitrile is a weaker solvent and alcohol is a stronger solvent. Various gradient and isocratic conditions can be used

Condition
Column Sharc 1, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN/MeOH – 95/5%
Buffer Ammonia 10mM
Flow Rate 005 ml/min
Detection UV, 250 nm

 

Description
Class of Compounds
  Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Benzoic Acid, Acetylbenzoic acid

 

Application Column

SHARC 1

The SHARC™ family of innovative columns represents the first commercially available columns primarily utilizing separation based on hydrogen bonding. SHARC stands for Specific Hydrogen-bond Adsorption Resolution Column. Hydrogen bonding involves an interaction or attraction between a bound hydrogen atom and molecules containing electronegative atoms, such as oxygen, nitrogen, and fluorine.

Select options
Application Analytes:
4-Acetylbenzoic Acid
Benzoic Acid
Application Detection:
ELSD Detection
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.