Cefradine

Cefradine structural formula

CAS Number38821-53-3
Molecular FormulaC16H19N3O4S
Molecular Weight349.411
InChI KeyRDLPVSKMFDYCOR-UEKVPHQBSA-N
LogP0.465
Synonyms
  • Cephradine
  • (6R,7R)-7-{[(2R)-2-Amino-2-(cyclohexa-1,4-dien-1-yl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
  • 38821-53-3
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
  • [6R-[6α,7β(R*)]]-7-Amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6α,7β(R*)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
  • 7-[D-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid
  • Cefradex
  • Cefradin
  • cefradina
  • cefradine
  • Cephradin
  • Cesporan
  • DESACETOXYCEPHALOSPORANIC ACID, 7-[D-2-AMINO-2-(1,4-CYCLOHEXADIENYL)ACETAMIDO-
  • Dimacef
  • Easkacef
  • Ecosporina
  • Eskacef
  • Lenzacef
  • Lisacef
  • Megacef
  • Samedrin
  • Velocef
  • Velosef
  • 7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic acid
  • BRN 6075388
  • EINECS 254-137-8
  • SKF D 39304
  • Velosef '125'
  • Velosef '250'
  • Velosef '500'
  • Cefradinum
  • UNII-9YA6SX5S4D
  • Cekodin
  • (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid
  • Anspor
  • CED
  • Sefril

Applications:

Uv-Vis Spectrum of Cefradine

January 14, 2026
Access the UV-Vis Spectrum SIELC Library
UV-Vis Spectrum of Cefradine.

If you are looking for optimized HPLC method to analyze Cefradine check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

 

Application Analytes:
Cefradine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Analysis of Cefradine

August 6, 2015

 

Cefradine is a drug used to treat bacterial infections of the respiratory or urinary tracts and skin or soft tissue. Legacy L1 was used to retain cefradine by reverse phase mechanism.Legacy L1 uses embedded C18 groups on porous silica and is useful for many USP HPLC applications. comparisons to Phenomenex columns are available by request.

 

Condition
Column Legacy L1, 4.6×250 mm, 5 µm, 100A
Mobile Phase MeOH – 15%
Buffer AmFm pH 3.0- 40 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm

 

Description
Class of Compounds
  Drug,  Hydrophilic, Ionizable
Analyzing Compounds Cefradine

 

Application Column

SIELC Legacy L1 HPLC column

Legacy L1

SIELC's family of Legacy columns is based on the United States Pharmacopeia's (USP) published chromatographic methods and procedures. Numerous brands have columns used in USP reference standards and methods. USP has created various designations to group together columns with similar types of packing and properties in the solid phase. SIELC's Legacy columns adhere to these strict requirements and properties, allowing you to easily replace older columns that are no longer available without needing to significantly modify your method or SOPs.

Select options
Application Analytes:
Cefradine
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.