MCPA

MCPA structural formula

CAS Number94-74-6
Molecular FormulaC9H9ClO3
Molecular Weight200.620
InChI KeyWHKUVVPPKQRRBV-UHFFFAOYSA-N
LogP3.25
Synonyms
  • MCPA
  • (4-Chloro-2-methylphenoxy)acetic acid
  • Acetic acid, 2-(4-chloro-2-methylphenoxy)-
  • 94-74-6
  • (4-Chloro-2-methylphenoxy) acetic acid
  • 2-Methyl-4-chlorophenoxyacetic acid
  • Acetic acid, (4-chloro-2-methylphenoxy)-
  • (2-Methyl-4-chlorophenoxy)acetic acid
  • (4-Chlor-2-methylphenoxy)essigsaure
  • (4-chloro-2-methylphenoxy)acetic acid
  • [(4-Chloro-o-tolyl)oxy]acetic acid
  • 4-Chloro-2-methylphenoxyacetic acid
  • 4-Chloro-o-tolyloxyacetic acid
  • Acetic acid, (4-chloro-o-toloxy)-
  • Acetic acid, [(4-chloro-o-tolyl)oxy]-
  • Acetic acid, 2-(4-chloro-2-methylphenoxy)-
  • Acide (4-chloro-2-methylphenoxy)acetique
  • acido (4-cloro-2-metilfenoxi)acetico
  • Agritox
  • Agroxon
  • Agroxone
  • Anicon kombi
  • Anicon M
  • B-Selektonon M
  • Chwastox 30
  • Dicopur M
  • Emcepan
  • Hedapur M 52
  • Hedarex M
  • Hedonal M
  • Herbicide M
  • Hormoneste
  • Leuna M
  • Mecaphar
  • Mephanac
  • Metaxon
  • Methoxone
  • Netazol
  • NSC 2351
  • Okultin M
  • PHENOXYACETIC ACID, 4-CHLORO-2-METHYL
  • U 46 M-fluid
  • Acme MCPA Amine 4
  • Banvel M
  • BH Mcpa
  • Bordermaster
  • BRN 2051752
  • Brominal M & plus
  • Caswell No. 557C
  • Chiptox
  • 4-Chloro-o-cresoxyacetic acid
  • 4-Chloro-o-toloxyacetic acid
  • ((4-Chloro-o-tolyl)oxy)acetic acid
  • Chwastox Extra
  • Cornox-M
  • Dicopur-M
  • EINECS 202-360-6
  • EPA Pesticide Chemical Code 030501
  • Hormotuho
  • Hornotuho
  • Krezone
  • Legumex DB
  • Leyspray
  • Linormone
  • Methylchlorophenoxyacetic acid
  • Phenoxylene 50
  • Phenoxylene plus
  • Phenoxylene super
  • Raphone
  • Razol dock killer
  • Rhomenc
  • Rhomene
  • Seppic MMD
  • Shamrox
  • Soviet technical herbicide 2M-4C
  • Ustinex
  • Vesakontuho MCPA
  • Weedar MCPA Concentrate
  • Weedone MCPA ester
  • Kwas 4-chloro-2-metylofenoksyoctowy
  • Kyselina 4-chlor-2-methylfenoxyoctova
  • UNII-D888C394VO
  • 2,4-MCPA
  • 2-Methyl-4-chlorphenoxyessigsaeure
  • MCP
  • [(4-Chloro-o-tolyl)oxy]acetic acid
  • 11111-13-0
  • 11111-14-1
  • 127289-40-1
  • 50926-55-1

Applications:

HPLC Separation of Pesticides, Herbicides, Fungicides and Insecticides on Newcrom BH Column

May 22, 2020


Herbicides are used to control unwanted plants, they are also known as weedkillers. Insecticides are used to kill insects. Fungicides are used to kill parasitic fungi. Pesticide is a more generic term that includes herbicides, fungicides and insecticides in its definition. All are heavily used in agriculture. By using HPLC, many different pesticides can be separated and their retention characteristics controlled using the Newcrom BH mixed-mode column. It can be used with different organic media such as acetonitrile (ACN) or methanol (MeOH). By varying the concentration of organic modifier and using different buffers like sulfuric acid (H2SO4), ammonium formate (AmFm), or formic acid, separation of desired pesticides can be achieved.

Condition

Column Newcrom BH, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN, MeOH
Buffer H2SO4, Formic acid, AmFm pH 3.0
Flow Rate 0.6 ml/min
Detection UV 275 nm

Description

Class of Compounds Pesticides, Herbicides, Fungicides, Insecticides
Analyzing Compounds Monocrotophos, Metribuzin, Bromacil, Carbofuran, 4-Chlorophenoxyacetic acid, Bentazone, Folpet, Fenthion, Fenvalerate, Metrabuzin, Carbofuran, Atrazine, Parathion –methyl, MCPA, Clopyralid, Dicamba, Benthazon, Simazine, Diuron, MCPB, Mecoprop, 4-Chlorophenoxyacetic acid,2,4,5-T

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2,4,5-Trichlorophenoxyacetic acid
4-CPA
Atrazine
Bentazone-sodium
Carbofuran
Clopyralid
Dicamba
Diuron
Fenvalerate
Folpet
MCPA
MCPB
Mecoprop
Methyl parathion
Metribuzin
Monocrotophos
Simazine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Analysis of MCPA on Primesep and Obelisc Mixed-Mode Columns

August 28, 2015

 

 

MCPA (4-Chloro-2-methylphenoxy)acetic acid) was synthesized to control broad-leaf weeds such as thistle and dock. MCPA forms complexes with metal ions and increase their bioavailability. A single residue method was developed and used by the EURL (European Union Reference Laboratory) for acidic pesticides. MCPA was separated by both Obelisc R and Primesep 100. Primesep 100 is a reverse-phase column with embedded acidic ion-pairing groups while Obelisc R is a mixed-mode column with separates using ionic groups and a long hydrophobic chain. Methods are LC/MS compatible and able to be used with many pesticides.

 

Condition 1

Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 25-70%, 15 min, 7 min hold
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min, 7 min hold
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Condition 2

Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min, 7 min hold
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min, 7 min hold
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Condition 3

Column Primesep 100, 2.1×150 mm, 3 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min, 7 min hold
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min, 7 min hold
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
Synthetic plant hormone, Acid,   Hydrophobic, Ionizable
Analyzing Compounds MCPA

 

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

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Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
MCPA
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.