Streptomycin

Streptomycin structural formula

CAS Number57-92-1
Molecular FormulaC21H39N7O12
Molecular Weight581.581
InChI KeyUCSJYZPVAKXKNQ-HZYVHMACSA-N
LogP-3.72
Synonyms
  • Streptomycin A
  • N,N'-[(1R,2R,3S,4R,5R,6S)-4-({5-Deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
  • Guanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-[[5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl]oxy]-2,5,6-trihydroxy-1,3-cyclohexanediyl]bis-
  • 57-92-1
  • D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1->4)-N,N'-bis(aminomethyl)-
  • 4-18-00-07540
  • D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-α-glucopyranosyl)-3-formylpentofuranoside
  • Agrimycin
  • D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N1,N3-bis(aminoiminomethyl)-
  • D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-
  • estreptomicina
  • Neodiestreptopab
  • NSC 14083
  • streptomycin
  • streptomycine
  • BRN 0074498
  • Caswell No. 804
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • EINECS 200-355-3
  • EPA Pesticide Chemical Code 006306
  • Hokko-mycin
  • Strepcen
  • Streptomycinum
  • Streptomicina
  • Streptomyzin
  • UNII-Y45QSO73OB
  • SM
  • [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
  • streomycin
  • 364062-67-9
  • 47814-83-5
  • 47816-81-9
  • 82958-69-8

Applications:

HPLC Determination of Streptomycin on Primesep 200 Column

May 9, 2019

HPLC Method for Streptothricins, Streptomycin B, Streptomycin on Primesep 200 by SIELC Technologies

HPLC Determination of Streptomycin sulfate salt on Primesep 200 Column

High Performance Liquid Chromatography (HPLC) Method for Analysis of Streptothricins, Streptomycin B, Streptomycin.

Streptomycin is an antibiotic used in treating bacterial infections and has also been used as a pesticide. It is on the World Health Organization’s (WHO) list of essential medicines. It works by inhibiting the synthesis of proteins. It can be retained on a Primesep 200 mixed-mode column by hydrophobic and ion-exchange properties. The analytical method uses MS-compatible mobile phase of acetonitrile (ACN) and water with sulfuric acid (H2SO4) buffer. Also capable of UV detection at 200nm.

Condition
Column Primesep 200
Mobile Phase MeCN/H2O – 10/90%
Buffer H2SO4 – 0.05%
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description
Class of Compounds
 Drug, Hydrophilic, Zwitterionic, Antibiotic
Analyzing Compounds Streptothricins, Streptomycin B, Streptomycin

 

Application Column

Primesep 200

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Streptomycin
Streptomycin B
Streptothricins
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.