Compound: Chlorpheniramine

Separation of Drugs in Mixed-Mode HPLC (I)

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Separation of Drugs in Mixed-Mode HPLC (II)

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Acetaminophen, chlorpheniramine and dextromethorphan are common drugs which are used together to reduce symptoms of cold and flu. Components of Coricidin formulation are separated on Obelisc R column with ELSD-LC/MS-UV compatible method. All peaks are well separated and retained.

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HPLC Separation of Drugs in Tylenol Cold and Cough Remedies

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Components of Tylenol Cold and Cough Remedy are separated on Obelisc R mixed-mode column. Method can be used to determine compounds in various cough and cold compositions. Neutral (acetaminophen), basic (chlorpheniramine, dextromethorphan and pseudoephedrine) and acidic (maleic acid/Maleate) components are analyzed with perfect peak shape and retention control. Method can be used in production, QC/QA and biological studies for quantitation of various components in pharmaceutical formulations (Advil, Tylenol, Dimetapp, Robitussin, NyQuil, etc)

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