| CAS Number | 375-22-4 |
|---|---|
| Molecular Formula | C4HF7O2 |
| Molecular Weight | 214.04 |
| InChI Key | YPJUNDFVDDCYIH-UHFFFAOYSA-N |
| LogP | 2.2 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Perfluorobutyric Acid
October 1, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze Perfluorobutyric Acid (PFBA) check our HPLC Applications library
UV/Vis.: λmax: 190 nm
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. This compound was diluted in a mixture of water and acetonitrile. The method was done with a mixture of water and acetonitrile.
HPLC Separation of Perfluoroalkyl Acids PFBA, PFAO, PEAS on Newcrom A Column
July 21, 2020
HPLC Method for Perfluorobutyric Acid (PFBA), Perfluorooctylsulfonic acid (PFAS), Perfluorooctanoic acid (PFOA) on Newcrom A by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Perfluorobutyric Acid (PFBA), Perfluorooctylsulfonic acid (PFAS), Perfluorooctanoic acid (PFOA).
Perfluoroalkyl acids (PFAAs) such as Perfluorobutyric acid, Perfluorononanoic acid and Perfluorooctylsulfonic acid are contaminants that have increasingly been found in groundwater and drinking water systems.
Perfluoroalkyl acids (PFAAs) are also strong surfactants that have been used industrially, in the production of fluoropolymers, but they are also present as residual impurities in a wide range of polymeric consumer products e.g. used to impart water and stain repellency in textiles, papers, and boards.
We were able to separate Perfluoroalkyl acids (PFAAs) in HPLC on Newcrom A mixed-mode column using a mobile phase of acetonitrile (ACN), and water with Ammonium Formate buffer. This separation can be monitored with ELSD, CAD detection techniques.
| Column | Newcrom A, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN – 40% |
| Buffer | AmFm pH 3.0 – 50 mM |
| Flow Rate | 1.0 ml/min |
| Detection | CAD |
| Class of Compounds | Perfluoroalkyl acids |
| Analyzing Compounds | Perfluorobutyric Acid (PFBA), Perfluorooctylsulfonic acid (PFAS), Perfluorooctanoic acid (PFOA) |
Application Column
Newcrom A
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Perfluorooctanoic acid (PFOA)
Perfluorooctylsulfonic acid (PFAS)
