CAS Number	739-71-9
Molecular Formula	C20H26N2
Molecular Weight	294.442
InChI Key	ZSCDBOWYZJWBIY-UHFFFAOYSA-N
LogP	4.92
Synonyms	Trimipramine 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl- 739-71-9 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,β-trimethyl- (.+-.)-Trimipramine 10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz[b,f]azepine 5-(γ-Dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine 5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro- Rhotrimine Sapilent Surmontil Trimeprimine Trimeproprimine Trimipramin trimipramina β-Methylimipramine 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)- 10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz(b,f)azepine 1-(3-Dimethylamino-2-methylpropyl)-4,5-dihydro-2,3:6,7-dibenzazepine 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine 5-(gamma-Dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine EINECS 212-008-3 2'-Metil-3'-dimetilamino-propil-5-iminodibenzile Trimeprimina Trimipraminum UNII-6S082C9NDT 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine 5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine RP-7162 beta-methylimipramine

Applications:

Uv-Vis Spectrum of Trimipramine

March 9, 2026

View Application

Access the UV-Vis Spectrum SIELC Library

If you are looking for optimized HPLC method to analyze Trimipramine check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

Trimipramine

SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Trimipramine

May 6, 2016

View Application

Trimipramine is a tricyclic antidepressant with antihistamine and sedative properties. It acts by decreasing the reuptake of norepinephrine and serotonin (5-HT), which is why it is used as treatment of major depressive disorder. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Trimipramine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options

Trimipramine
Trimipramine maleate

UV Detection