3-Iodo-2-propynyl-N-butylcarbamate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Iodopropynyl Butyl Carbamate is a water-based preservative used in paints, coating, personal care and cosmetic industries. It is used because of its fungicide properties. It can be retained on Newcrom R1 reverse-phase column using an isocratic analytical method using a mobile phase of acetonitrile (ACN) and water with a phosphoric acid (H3PO4) buffer with UV detection at 200nm.