6-Methyl-5-hepten-2-one can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Sulcatone is a ketone used as a mosquito attractant. It is a volatile oil component found in
citrus. It can be retained on a Newcrom R1reverse-phase column with a mobile phase of acetonitrile (ACN) and water with sulfuric acid (H2SO4) buffer. The analytical method is MS-compatible and can also use UV detection at 200nm.