8-Hydroxyquinoline

CAS Number 148-24-3
Molecular Formula C9H7NO
Molecular Weight 145.161 g/mol
InChI Key MCJGNVYPOGVAJF-UHFFFAOYSA-N
LogP 2.02
Synonyms
  • 8-Hydroxyquinoline
  • Quinolin-8-ol
  • 8-Quinolinol
  • 148-24-3
  • Oxyquinoline
  • 8-Quinolinol
  • 5-21-03-00252
  • 1-Azanaphthalene-8-ol
  • 8-Hydroxychinolin
  • 8-Oxyquinoline
  • Albisal
  • Chinolin-8-ol
  • Fennosan H 30
  • HYDROXYQUINOLINE
  • NSC 2039
  • NSC 285166
  • NSC 402623
  • NSC 48037
  • NSC 54230
  • NSC 615011
  • NSC 82404
  • NSC 82405
  • NSC 82409
  • NSC 82410
  • NSC 82412
  • Oxoquinoline
  • Oxychinolin
  • Phenopyridine
  • Quinolein-8-ol
  • quinoleine-8-ol
  • quinolin-8-ol
  • QUINOLINE, 8-HYDROXY-
  • Quinophenol
  • BRN 0114512
  • Caswell No. 719
  • EINECS 205-711-1
  • EPA Pesticide Chemical Code 059803
  • Fennosan
  • Fennosan HF-15
  • Hydroxybenzopyridine
  • NCI-C55298
  • Oxybenzopyridine
  • USAF EK-794
  • o-Oxychinolin
  • UNII-5UTX5635HP
  • 8-Chinolinol
  • 8-Hydroxy-chinolin
  • 8-OQ
  • 8-Quinol
  • 123574-67-4
  • 24804-14-6

Applications:


HPLC Method for Analysis of 8-hydroxyquinoline
8-hydroxyquinoline HPLC analysis of 8-Hydroxyquinoline is complicated due to chelating properties of this chemical. 8-Hydroxyquinoline forms complex with many transition metal ions and as result it used often to measure amount of metal contamination on silica based columns.
Even small amount of metal ions on silica surface cause peak distortion with low peak efficiency and poor symmetry.
The same chemical can be analysed on Primesep 200 column with simple method based on acetonitrile-water mixture and phosphoric acid as ionic modifier.  High efficiency and symmetrical peak shape is obtained. For mass-spectroscopy detection (LC-MS) phosphoric acid can be substituted with ammonium format to get similar result.
 
Primesep 200 also offers much more retention compare to any C18 column due to ionic interaction of basic quinoline molecule with cation-exchange functional groups of the Primesep 200 stationary phase.

Application Analytes:

8-Hydroxyquinoline