gamma-Cyclodextrin

CAS Number17465-86-0
Molecular FormulaC48H80O40
Molecular Weight1297.1
InChI KeyGDSRMADSINPKSL-HSEONFRVSA-N
LogP-17.2
Synonyms
  • cyclomalto-octaose
  • cyclomaltooctaose
  • cyclooctaamylose
  • gamma-cyclodextrin
  • gamma-Cyclodextrin
  • Cyclooctaamylose
  • 17465-86-0
  • gamma cyclodextrin
  • Cyclooctapentylose
  • Cyclomaltooctaose
  • gamma-Dextrin
  • Ringdex C
  • gamma-CD

Applications:

HPLC Method For Analysis of Cyclodextrins on Primesep S2

September 29, 2021

HPLC Method for beta-CYCLODEXTRIN, alpha-CYCLODEXTRIN, gamma-Cyclodextrin on Primesep S2 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of B-Cyclodextrin, G-Cyclodextrin and A-Cyclodextrin

Cyclodextrins are hexasaccharides that are natural starch-conversion products. Industrially, they are manufactured by enzymatic degradation of vegetable raw materials.

Alpha-cyclodextrin has the chemical formula C36H60O30. It is said to lower blood pressure, cholesterol, and glucose levels. It is primarily used as a dietary supplement for fiber.

Beta-cyclodextrin has the chemical formula C42H70O35. It is used in a large variety of industries primarily as a complexing agent.  It’s most notable uses are in medicine as sustained release drugs carrier and to improve stability in drugs.

Gamma-cyclodextrin has the chemical formula C48H80O40. It is used as a complexing agent due to having the largest cavity size between the natural cyclodextrin. It has use across a variety of industries from food, to medicine, to textiles, and cosmetics.

Condition
Column Primesep S2, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN- 70%
Buffer AmFm pH 3.0- 20 mm
Flow Rate 1.0 ml/min
Detection ELSD

Description
Class of Compounds Sugar
Analyzing Compounds beta-CYCLODEXTRIN, alpha-CYCLODEXTRIN, gamma-Cyclodextrin

 

Application Column

Primesep S2

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
alpha-CYCLODEXTRIN
beta-CYCLODEXTRIN
gamma-Cyclodextrin
Application Detection:
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.