L-Isoleucine

CAS Number73-32-5
Molecular FormulaC6H13NO2
Molecular Weight131.175
InChI KeyAGPKZVBTJJNPAG-WHFBIAKZSA-N
LogP-0.720
Synonyms
  • 2S,3S)-?-Amino-?-methyl-n-valeric acid
  • (2S,3S)-?-Amino-?-methylvaleric acid
  • (S)-Isoleucine
  • (S,S)-Isoleucine
  • [S-(R*,R*)]-2-Amino-3-methylpentanoic acid
  • 2-Amino-3-methylvaleric acid
  • 2S,3S-Isoleucine
  • erythro-L-Isoleucine
  • Isoleucine
  • ISOLEUCINE, L-
  • L-(+)-Isoleucine
  • L-Isoleucin
  • L-isoleucina
  • L-Norvaline, 3-methyl-, erythro-
  • NSC 46708
  • Pentanoic acid, 2-amino-3-methyl-, (2S,3S)-
  • Secretory protein (human clone HCEEE79 precursor)
  • Acetic acid, amino-sec-butyl-
  • Acetic acid, amino(1-methylpropyl)-, (R*,R*)-
  • (S-(R*,R*))-2-Amino-3-methylpentanoic acid
  • 2-Amino-3-methylpentanoic acid, (S-(R*,R*))-
  • EINECS 200-798-2
  • Norvaline, 3-methyl-
  • Pentanoic acid, 2-amino-3-methyl-
  • Pentanoic acid, 2-amino-3-methyl-, (S-(R*,R))-
  • Valeric acid, 2-amino-3-methyl-
  • Isoleucina
  • Isoleucinum
  • UNII-04Y7590D77 FDA Registry Number
  • (2S,3S)-2-Amino-3-methylpentanoate
  • (2S,3S)-2-amino-3-methyl-Pentanoate
  • (2S,3S)-2-amino-3-methyl-pentanoic acid
  • (2S,3S)-a-Amino-b-methyl-N-valerate
  • (2S,3S)-a-Amino-b-methyl-N-valeric acid
  • (2S,3S)-a-Amino-b-methylvalerate
  • (2S,3S)-a-Amino-b-methylvaleric acid
  • (2S,3S)-alph-Amino-beta-methylvalerate
  • (2S,3S)-alph-Amino-beta-methylvaleric acid
  • (2S,3S)-alpha-Amino-beta-merthyl-N-valerate
  • (2S,3S)-alpha-Amino-beta-merthyl-N-valeric acid
  • (2S,3S)-alpha-Amino-beta-merthylvalerate
  • (2S,3S)-alpha-Amino-beta-merthylvaleric acid
  • (2S,3S)-alpha-Amino-beta-methyl-N-valerate
  • (2S,3S)-alpha-Amino-beta-methyl-N-valeric acid
  • (2S,3S)-alpha-Amino-beta-methylvalerate
  • (2S,3S)-alpha-Amino-beta-methylvaleric acid
  • 2-Amino-3-methylpentanoate
  • 2-Amino-3-methylpentanoic acid
  • 2-Amino-3-methylvalerate
  • Iso-leucine

Applications:

HPLC Separation of Allo-Isoleucine, Isoleucine, Leucine on Primesep 100 Column

November 12, 2019


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HPLC Separation of Allo-Isoleucine  Isoleucine, Leucine on Primesep 100 Column Chr_1197

Condition

Column Primesep 100, 4.6×250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 5/95%
Buffer AmFM pH 3.0 – 30 mM
Flow Rate 1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase

 

Description

Class of Compounds
Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Allo-Isoleucine, Isoleucine, Leucine

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
D-Isoleucine
D-Leucine
DL-Isoleucine
Isoleucine
L-Alloisoleucine
L-Isoleucine
Leucine
allo-D-isoleucine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of Mixture of Essential Amino Acids on Primesep 100 Column

March 11, 2019

 

Condition

Column Primesep 100, 4.6×250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 25/75%
Buffer Gradient H2SO4 0.05-0.2% 25 min
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds L-Threonine (Thr/T), L-Valine (Val/V), DL-Methionine (Met/M), L-Isoleucine (Ile/I), L-Leucine (Leu/L), L-Phenylalanine (Phe/F), L-Histidine (His/H), L- Tryptophan (Trp/W)

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Amino Acids
D-Isoleucine
D-Leucine
D-Valine
DL-Isoleucine
Histidine
Isoleucine
L-Histidine hydrochloride monohydrate
L-Isoleucine
L-Methionine
L-Threonine
Methionine
Phenylalanine
Tryptophan
Valine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of allo-D-isoleucine and L- Isoleucine

March 20, 2018

Condition

Column Primesep 100, Primesep 200 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer TFA, FA
Flow Rate 1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase

 

Description

Class of Compounds
Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Allo-Isoleucine, Isoleucine, Leucine

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Isoleucine
L-Isoleucine
allo-D-isoleucine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.