Ethylene Glycol

CAS Number107-21-1
Molecular FormulaC2H6O2
Molecular Weight62.07
InChI KeyLYCAIKOWRPUZTN-UHFFFAOYSA-N
LogP-1.4
Synonyms
  • ETHYLENE GLYCOL
  • 1,2-ethanediol
  • Ethane-1,2-diol
  • 107-21-1
  • glycol
  • monoethylene glycol
  • 1,2-Dihydroxyethane
  • 2-hydroxyethanol
  • Glycol alcohol
  • polyethylene glycol
  • Ethylene alcohol
  • Macrogol
  • Fridex
  • Tescol
  • Ethylene dihydrate
  • Norkool
  • Macrogol 400 BPC
  • Dowtherm SR 1
  • ethanediol
  • Zerex
  • Ucar 17
  • Lutrol-9
  • Polyethylene glycol 200
  • Aethylenglykol
  • 1,2-Ethandiol
  • Poly(ethylene glycol)
  • MFCD00002885
  • Ethylenglycol
  • ethylen glycol
  • ethylene-glycol
  • Polyethylene glycol 600
  • 146AR
  • Polyethylene glycol 1000
  • Polyethylene glycol 3350
  • UNII-FC72KVT52F
  • Lutrol 9
  • NSC 93876
  • Carbowax 300
  • 1,2-ethylene glycol
  • 1,2-dihydroxy ethane
  • HOCH2CH2OH
  • Union Carbide XL 54 Type I De-icing Fluid
  • M.e.g.
  • PEG
  • Polyethylene Glycol 4000
  • FC72KVT52F
  • DTXSID8020597
  • CHEBI:30742
  • 1, 2-Ethanediol
  • DSSTox_CID_597
  • H(OCH2CH2)nOH
  • Ethylene glycol, technical
  • Polyethylene oxide
  • DSSTox_RID_75680
  • DSSTox_GSID_20597
  • Glycol, ethylene-
  • Glycol, polyethylene
  • Glycols, polyethylene
  • Caswell No. 441
  • Miralax
  • Aethylenglykol [German]
  • Ethylene glycol, 99.5%, for analysis
  • Carbowax 20
  • CAS-107-21-1
  • Polyethylene Glycols
  • Carbowax 400
  • Carbowax 1000
  • CCRIS 3744
  • Dowtherm 4000
  • HSDB 5012
  • Ethylene glycol polymer
  • NCI-C00920
  • Ethylene glycol, 99.8%, anhydrous, AcroSeal(R)
  • PEG 3350
  • EINECS 203-473-3
  • Ethylene glycol homopolymer
  • Polyethylene Glycol 6000
  • EPA Pesticide Chemical Code 042203
  • 1,2-Ethanediol homopolymer
  • ethyleneglycole
  • Athylenglykol
  • ehtylene glycol
  • etylene glycol
  • AI3-03050
  • 2-ethanediol
  • Polyaethylenglykol
  • Ilexan E
  • 4-vinyl cathecol
  • Polyaethylenglykole
  • MEG 100
  • Solbanon (TN)
  • 1,2-ethane diol
  • 1,2-ethane-diol
  • ethane-1.2-diol
  • GXT
  • PEG 1000
  • PEG 4000
  • 1,2-ethyleneglycol
  • ethan-1,2-diol
  • mono-ethylene glycol
  • Macrogol 400
  • Mono Ethylene Glycol
  • Carbowax 1540
  • 1,2-ethylene-glycol
  • Lutrol E (TN)
  • DuPont Zonyl FSO Fluorinated Surfactants
  • alpha-Hydro-omega-hydroxypoly(oxyethylene)
  • polyethylene glycol-400
  • Macrogol 400 (TN)
  • Polyethylene oxide (NF)
  • Polyethylene glycol (NF)
  • ACMC-1AS4X
  • Sentry polyox WSR (TN)
  • Macrogol 1500 (TN)
  • Macrogol 4000 (TN)
  • Macrogol 6000 (TN)
  • EC 203-473-3
  • Macrogol ointment (JP17)
  • WLN: Q2Q
  • 2-$l^{1}-oxidanylethanol
  • Glycol, polyethylene(300)
  • HO(CH2)2OH
  • NCIOpen2_001979
  • NCIOpen2_002019
  • NCIOpen2_002100
  • Macrogol 400 (JP17)
  • Polyethylene Glycol 300 NF
  • alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
  • Ethylene glycol 5 M solution
  • MLS002454404
  • Polyethylene glycol, diglycidyl bisphenol A polymer
  • BIDD:ER0283
  • FisherFresh™ Concentrate
  • Macrogol 1500 (JP17)
  • Macrogol 4000 (JP17)
  • Macrogol 6000 (JP17)
  • 1,2-Ethanediol-d2 (9CI)
  • CHEMBL457299
  • DTXSID4027862
  • Ethylene glycol, AR, >=99%
  • Ethylene glycol, LR, >=99%
  • Macrogol 20000 (JP17)
  • CHEBI:46793
  • PEG1000
  • Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-
  • HMS2267F07
  • Poly(ethylene glycol) methyl ether
  • Polyethylene glycol 3350 (USP)
  • WT931
  • Ethylene glycol, p.a., 99.5%
  • 1,2-bis($l^{1}-oxidanyl)ethane
  • 1,2-ETHANEDIOL (GLYCOL)
  • AMY22336
  • NSC32853
  • NSC32854
  • NSC57859
  • NSC93876
  • PEG 3600
  • PEG-1000
  • poly (ethylene glycol) methyl ether
  • ZINC5224354
  • Ethylene glycol, analytical standard
  • Tox21_202038
  • Tox21_300637
  • ANW-15497
  • Ethane-1,2-diol (Ethylene Glycol)
  • Ethylene glycol, anhydrous, 99.8%
  • NSC-32853
  • NSC-32854
  • NSC-57859
  • NSC-93876
  • NSC152324
  • NSC152325
  • NSC155081
  • Polyethylene Glycol 8000, NF FCC
  • STL264188
  • M.W range 3,000-3,700
  • AKOS000119039
  • ETHYLENE GLYCOL, [1,2-3H]
  • alpha,omega-hydroxypoly(ethylene oxide)
  • MCULE-6366313128
  • NSC-152324
  • NSC-152325
  • NSC-155081
  • 61266-70-4 2-Hydroxymethyloxethane
  • Ethylene glycol, Spectrophotometric grade
  • NCGC00091510-01
  • NCGC00091510-02
  • NCGC00091510-03
  • NCGC00254292-01
  • NCGC00259587-01
  • AK116144
  • BP-13454
  • BP-31056
  • M430
  • Oxirane, 2,2'-((1-methylethylidene)bis(4,1-phenyleneoxymethylene))bis-, polymer with alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
  • SMR001262244
  • Dihydrocarveol, (-)-, mixture of isomers
  • ETHYLENE GLYCOL HIGH PURITY GRD 1L
  • Ethylene glycol, ReagentPlus(R), >=99%
  • DuPont Zonyl FSE Fluorinated Surfactants
  • Residual Solvent Class 2 - Ethylene Glycol
  • 242-EP2269996A1
  • 242-EP2272826A1
  • 242-EP2272846A1
  • 242-EP2272849A1
  • 242-EP2275413A1
  • 242-EP2275420A1
  • 242-EP2277867A2
  • 242-EP2280003A2
  • 242-EP2281810A1
  • 242-EP2281812A1
  • 242-EP2284165A1
  • 242-EP2286812A1
  • 242-EP2287156A1
  • 242-EP2289897A1
  • 242-EP2292597A1
  • 242-EP2292608A1
  • 242-EP2295399A2
  • 242-EP2295434A2
  • 242-EP2295438A1
  • 242-EP2298076A1
  • 242-EP2298077A1
  • 242-EP2298750A1
  • 242-EP2298770A1
  • 242-EP2301353A1
  • 242-EP2305031A1
  • 242-EP2305034A1
  • 242-EP2305035A1
  • 242-EP2305663A1
  • 242-EP2305673A1
  • 242-EP2305683A1
  • 242-EP2308510A1
  • 242-EP2308857A1
  • 242-EP2308866A1
  • 242-EP2308877A1
  • 242-EP2311804A2
  • 242-EP2311807A1
  • 242-EP2311834A1
  • 242-EP2311839A1
  • 242-EP2314574A1
  • 242-EP2314589A1
  • 242-EP2316837A1
  • 242-EP2371797A1
  • 242-EP2371798A1
  • 242-EP2371800A1
  • 242-EP2371804A1
  • 242-EP2371809A1
  • 242-EP2374895A1
  • 242-EP2377845A1
  • 242-EP2380873A1
  • 378-EP2269977A2
  • 378-EP2270010A1
  • 378-EP2270017A1
  • 378-EP2270101A1
  • 378-EP2270113A1
  • 378-EP2272813A2
  • 378-EP2272817A1
  • 378-EP2272832A1
  • 378-EP2272849A1
  • 378-EP2272935A1
  • 378-EP2272972A1
  • 378-EP2272973A1
  • 378-EP2274983A1
  • 378-EP2275395A2
  • 378-EP2275404A1
  • 378-EP2275417A2
  • 378-EP2275425A1
  • 378-EP2275469A1
  • 378-EP2277507A1
  • 378-EP2277622A1
  • 378-EP2277858A1
  • 378-EP2277866A1
  • 378-EP2277867A2
  • 378-EP2277872A1
  • 378-EP2277875A2
  • 378-EP2280003A2
  • 378-EP2281563A1
  • 378-EP2281810A1
  • 378-EP2281818A1
  • 378-EP2281821A1
  • 378-EP2281824A1
  • 378-EP2284157A1
  • 378-EP2284159A1
  • 378-EP2284162A2
  • 378-EP2284163A2
  • 378-EP2284165A1
  • 378-EP2284169A1
  • 378-EP2286795A1
  • 378-EP2286811A1
  • 378-EP2287161A1
  • 378-EP2287162A1
  • 378-EP2287940A1
  • 378-EP2289965A1
  • 378-EP2292592A1
  • 378-EP2292597A1
  • 378-EP2292606A1
  • 378-EP2292621A1
  • 378-EP2295055A2
  • 378-EP2295399A2
  • 378-EP2295416A2
  • 378-EP2295438A1
  • 378-EP2295439A1
  • 378-EP2298735A1
  • 378-EP2298743A1
  • 378-EP2298747A1
  • 378-EP2298748A2
  • 378-EP2298760A1
  • 378-EP2298767A1
  • 378-EP2298768A1
  • 378-EP2298770A1
  • 378-EP2298772A1
  • 378-EP2298778A1
  • 378-EP2298828A1
  • 378-EP2301924A1
  • 378-EP2301933A1
  • 378-EP2301941A1
  • 378-EP2301983A1
  • 378-EP2305625A1
  • 378-EP2305627A1
  • 378-EP2305642A2
  • 378-EP2305651A1
  • 378-EP2305658A1
  • 378-EP2305667A2
  • 378-EP2305808A1
  • 378-EP2308839A1
  • 378-EP2308843A1
  • 378-EP2308854A1
  • 378-EP2308857A1
  • 378-EP2308858A1
  • 378-EP2308861A1
  • 378-EP2308865A1
  • 378-EP2308926A1
  • 378-EP2309564A1
  • 378-EP2311453A1
  • 378-EP2311815A1
  • 378-EP2311816A1
  • 378-EP2311817A1
  • 378-EP2311818A1
  • 378-EP2311827A1
  • 378-EP2314558A1
  • 378-EP2314576A1
  • 378-EP2314577A1
  • 378-EP2314587A1
  • 378-EP2315303A1
  • 378-EP2316831A1
  • 378-EP2371799A1
  • 378-EP2371809A1
  • 378-EP2371811A2
  • 378-EP2372017A1
  • 378-EP2374783A1
  • 378-EP2374786A1
  • 378-EP2374790A1
  • 378-EP2374895A1
  • 378-EP2377841A1
  • 378-EP2380873A1
  • E0105
  • Ethylene glycol 1000 microg/mL in Methanol
  • Ethylene glycol, puriss., >=99.5% (GC)
  • FT-0626292
  • FT-0692978
  • 1,2-Ethane-1,1,2,2-d4-diol-d2(9ci)
  • Ethylene glycol, BioUltra, >=99.5% (GC)
  • Ethylene glycol, SAJ first grade, >=99.0%
  • C01380
  • C15588
  • D03370
  • D06418
  • D06419
  • D06420
  • D06421
  • D06422
  • D06423
  • Ethylene glycol, JIS special grade, >=99.5%
  • 27283-EP2270007A1
  • 27283-EP2270505A1
  • 27283-EP2272817A1
  • 27283-EP2272822A1
  • 27283-EP2279750A1
  • 27283-EP2280000A1
  • 27283-EP2281823A2
  • 27283-EP2284160A1
  • 27283-EP2284169A1
  • 27283-EP2287160A1
  • 27283-EP2287161A1
  • 27283-EP2287162A1
  • 27283-EP2292612A2
  • 27283-EP2305673A1
  • 27283-EP2308510A1
  • 27283-EP2308562A2
  • 27283-EP2308877A1
  • 27283-EP2311832A1
  • 27283-EP2311833A1
  • 27283-EP2311834A1
  • 27283-EP2314575A1
  • 27283-EP2371811A2
  • 27283-EP2374790A1
  • 27283-EP2377849A2
  • 89779-EP2289483A1
  • 89779-EP2295422A2
  • 89779-EP2305033A1
  • Ethylene glycol, anhydrous, ZerO2(TM), 99.8%
  • Ethylene glycol, Vetec(TM) reagent grade, 98%
  • Ethylene glycol, spectrophotometric grade, >=99%
  • Q194207
  • J-001731
  • F0001-0142
  • 004143F9-240E-472F-9D5A-B1B13BBA2A18
  • Ethylene glycol, United States Pharmacopeia (USP) Reference Standard
  • Ethylene glycol, Pharmaceutical Secondary Standard; Certified Reference Material
  • 76550-74-8
  • Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
  • Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
  • ethylene glycol;1,2-ethanediol;ethane-1,2-diol;glycolethylene glycol;ethanediol;ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol

Applications:

HPLC Method For Analysis of Ethylene Glycol and Polyethylene Glycol (PEG) on Primesep AP Column

September 14, 2021

Separation type: Liquid Chromatography HILIC


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High Performance Liquid Chromatography (HPLC) Method for Analysis of Ethylene glycol, PEG 200, PEG 400.

Polyethylene glycol (PEG) has a low toxicity and is used in a variety of products (creams, laxatives, lubricants). When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. This makes for a longer acting medicinal effect, reduces toxicity, and allows longer dosing intervals. HILIC separation can be used to determine polyethylene glycol content in various formulations using ELSD, RI detection, or LC/MS detection. HPLC separation of oligomers can be achieved by changing the amount of acetonitrile.

Condition

 

Column Primesep AP, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 95/5%
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 200 nm, RI

 

Description

Class of Compounds
Diol
Analyzing Compounds Ethylene glycol, PEG 200, PEG 400

 

Application Column

Primesep AP

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Ethylene Glycol
Polyethylene Glycol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method  For Simultaneous Quantification of Sugar Alcohols (Polyols) on Primesep AP

September 9, 2021

Separation type: Liquid Chromatography HILIC


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High Performance Liquid Chromatography (HPLC) Method for Analysis of Ethylene glycol, Glycerol, Erythritol, Xylitol, Sorbitol.

Condition

Column Primesep AP, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 75/25%
Buffer No
Flow Rate 1.0 ml/min
Detection UV 200 nm, RI

 

Description

Class of Compounds
Drug, Basic, Hydrophobic, Ionizable, Zwitterionic
Analyzing Compounds Ethylene glycol, Glycerol, Erythritol , Xylitol, Sorbitol

 

Application Column

Primesep AP

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Erythritol
Ethylene Glycol
Glycerol
Sorbitol
Xylitol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.