Captan is a phthalimide fungicide which is typically used as a component in industrial pesticide mixtures. The EURL included a QuEChERS (Quick, Easy, Cheap, Rugged, and Safe) method for captan as a target pesticide for EUPT-SRM. Obelisc R was used to retain captan and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing captan.