Simultaneous Determination of Sodium and Sulfate Ions on Obelisc N Mixed-mode HILIC Column

Inorganic cations and anions are usually analyzed by two different methods - cation-exchange and anion-exchange. This requires development and validation of two methods. Both ions can be analyzed on mixed-mode HILIC column with ELSD detection. Both ions are retained by combination of HILIC and ion-exchange mechanism.

Condition

Column Obelisc N, 4.6x50 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer AmFm, pH 3.0
Flow Rate 1.0 ml/min
Detection ELSD
 

Description

Class of Compounds Acid, Hydrophilic, Ionizable
Analyzing Compounds Sodium, Sulfate Ions
 

Application Analytes:

Sodium
Sulfate