Application Notes: Aminocaproic acid is a enzymatic inhibitor. According to USP methods, aminocaproic acid conatins not less than 98.5% and not more than 101.5% of aminocaproic acid calculated on a dried basis. The USP HPLC method for the separation of aminocaproic acid was developed on Legacy L1 column according to the US Pharmacopeia methodology. L1 classification is assigned to reversed-phase HPLC column containing C18 ligand. Support for the material is spherical silica gel with particles size 3-10 um and pore size of 100-120A. Resolution between critical pairs corresponds to rules and specifications of UPS.
Application Columns: Legacy L1 C18 HPLC column
Application compounds: Aminocaproic acid
Mobile phase: Sodium heptanesulfonate/H2O/MeOH /NaH2PO4 pH 2.2
Detection technique: UV
Reference: USP35: NF30
| Column | Legacy L1, 4.6x150 mm, 5 µm, 100A |
| Mobile Phase | Sodium heptanesulfonate/H2O/MeOH /NaH2PO4 pH 2.2 |
| Flow Rate | 0.7 ml/min |
| Detection | UV, 210 nm |
| Class of Compounds | Drug, Clotting promoter, Hydrophilic, Ionizable |
| Analyzing Compounds | Aminocaproic Acid |
Application Analytes:
Aminocaproic acid