Atorvastatin

CAS Number 134523-00-5
Molecular Formula C33H35FN2O5
Molecular Weight 558.650 g/mol
InChI Key XUKUURHRXDUEBC-KAYWLYCHSA-N
LogP 5.04
Synonyms
  • Atorvastatin
  • (3R,5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (betaR,deltaR)-
  • 134523-00-5
  • Cardyl
  • Atorvastatin acid
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-
  • (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
  • (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid
  • Tozalip
  • Xavator
  • UNII-A0JWA85V8F
  • (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
  • Atorvastatin calcium
  • Lipitor

Applications:


HPLC Separation of Fungicides in a Green Tea Matrix

 

Even though teas are known for containing polyphenols such as catechins, flavonoids and theaflavins, SIELC mixed-mode columns can be used to analyze a matrix from a commercial tea and retain target compounds. In this method, green tea was spiked with 0.005mg/ml of pesticides previously found in teas. Primesep 200 was used for it’s reverse-phase and acidic ion-pairing groups. Target compounds were retained and resolved from the majority of the tea matrix peak.



Application Analytes:

Atorvastatin
Picoxystrobin
Pyrimethanil

HPLC Separation of Agricultural Compounds Found in Tea

 

Tea has been known to contain residue of pesticides and fungicides such as picoxystrobin and pyrimethanil. We used Primesep 200, a reversed-phase column with weakly acidic ion-pairing groups to separate picoxystrobin, pyrimethanil and atorvastatin. A 15 minute method used to demonstrate retention control when adjusting ratio of organic to aqueous in the mobile phase. Baseline retention with good resolution was achieved.  



Application Analytes:

Atorvastatin
Picoxystrobin
Pyrimethanil

HPLC Method for Analysis of Lipitor
Chr_1069

Application Analytes:

Atorvastatin
Lipitor

HPLC Method for Analysis of Atorvastatin


Application Analytes:

Atorvastatin
Lipitor