CAS Number 2387-59-9
Molecular Formula C5H9NO4S
Molecular Weight 179.190 g/mol
LogP -1.65
  • Carbocysteine
  • S-(Carboxymethyl)cysteine
  • Cysteine, S-(carboxymethyl)-
  • 2387-59-9
  • Cysteine, S-(carboxymethyl)-


HILIC Separation of Carboxymethylcysteine and Betaine

In this HPLC method, betaine and carboxymethylcysteine are separated by HILIC mixed-mode mechanism. Betaine and carboxymethylcysteine are very hydrophilic compounds which are not retained on reverse phase columns. Compounds are separated by combination of HILIC and ion-exchange mechanisms. In HIILIC mode, Obelisc N columns allow operating at lower organic concentration for improved solubility of analytes. Method can be used for quantitative or qualitative analysis of betaine and carboxymethylcysteine using ESLD or LC/MS detection. Betaine in chemistry is any neutral chemical compound with a positively charged cationic functional group such as ammonium ion or phosphonium ion (generally: onium ions) which bears no hydrogen atom and with a negatively charged functional group such as a carboxylate group which may not be adjacent to the cationic site. Historically the term was reserved for tetramethylglycine only.

Application Analytes: