Citrulline

CAS Number 372-75-8
Molecular Formula C6H13N3O3
Molecular Weight 175.188 g/mol
InChI Key RHGKLRLOHDJJDR-BYPYZUCNSA-N
LogP -3.13
Synonyms
  • Citrulline
  • N5-Carbamoyl-L-ornithine
  • L-Ornithine, N5-(aminocarbonyl)-
  • 372-75-8

Applications:


HPLC Separation of Citrulline and Arginine
               
Citrulline and Arginine are α-amino acids that differ only in one functional group. They can be separated on a reverse-phase Primesep 200 HPLC column by hydrophobic and cation-exchange mechanisms in a mobile phase of water and acetonitrile (MeCN, ACN) with a gradient buffer of formic acid. Evaporative Light Scattering Detector (ELSD) used.  

Application Analytes:

Arginine
Citrulline
Sodium

HPLC Analysis of Citrulline and Arginine on Primesep Columns


Two underivatized amino acids, citrulline and arginine, are separated by mixed-mode chromatography on Primesep 100 and Primesep 200 HPLC columns with LC/MS compatible mobile phase. Method can be used for retention and separation of underivatized amino acids without ion-pairing reagent in the mobile phase.



Application Analytes:

Arginine
Citrulline