Cytidine Diphosphate

Cytidine Diphosphate

CAS Number 63-38-7
Molecular Formula C9H15N3O11P2
Molecular Weight 403.177 g/mol
LogP -4.5
  • Cytidine 5'-diphosphate
  • Cytidine diphosphate
  • cytidine-5'-diphosphate
  • Cytidine 5'-(trihydrogen diphosphate)
  • 63-38-7
  • Cytidine coenzyme
  • Cytidine 5'-pyrophosphate
  • 5'-CDP
  • Cytidine 5'-diphosphoric acid
  • CDP
  • Cytidine 5'-pyrophosphoric acid
  • UNII-1ZH821MXU5
  • cytidine-diphosphate
  • BRN 0063920
  • Cytidine pyrophosphate
  • EINECS 200-557-1
  • 1ZH821MXU5
  • CHEMBL425252
  • CHEBI:17239
  • AK115810
  • 34393-59-4
  • CDF
  • cytidine trihydrogen diphosphate
  • C9H15N3O11P2
  • Cytidine 5 -diphosphate
  • [3h]cytidine diphosphate
  • bmse000272
  • AC1L1LV6


HPLC Separation of Cytidines

Cytidine phosphates are nucleotides. Nucleotides contain a nucleobase, five-carbon sugar and one or three phosphate groups. All three cytidines are very polar and cannot be retained by reversed-phase chromatography without a ion-pairing reagent. Mixed-mode Primesep SB column easily allows to retain and separate mono-, di-, and tri-phospates by anion-exchange mechanism. Other nucleotides can be separated as well by this approach. Nucleotides in biofluids can be analyzed directly on this column without any significant sample preparation. Most of the proteins from biological fluids will be repelled from the surface of silica gel. Method is compatible with UV, ELSD, CAD and LC/MS.

Application Analytes:

Cytidine Diphosphate
Cytidine Monophosphate
Cytidine Triphosphate

Separation of Nine Nucleotides by Mixed-Mode Chromatography
  Nucleotides are important biological molecules which serve as subunits of nucleic acids. They are composed of a five-carbon sugar, a nitrogenous base, and at least one phosphate group. Nucleotides cannot be retained by reverse-phase chromatography without an ion-pairing reagent due to their highly polar nature. Primesep SB is capable of retaining and separating nine nucleotides. Primesep SB is a reverse-phase column with strong embedded basic ion-pairing groups.

Application Analytes:

Adenosine Diphosphate
Adenosine Monophosphate
Adenosine Triphosphate
Cytidine Diphosphate
Cytidine Monophosphate
Cytidine Triphosphate
Guanosine Diphosphate
Guanosine Monophosphate
Guanosine Triphosphate

HPLC Separation of Cytidine-5'-monophosphate (CDP) and Adenosine 5'-Triphosphate (ATP) on Newcrom B Column View on


Column Newcrom B, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/85%
Buffer Formic Acid -  5%
Flow Rate 1.0 ml/min
Detection UV 270nm


Class of Compounds Acid, Hydrophilic, Ionizable
Analyzing Compounds Adenosine 5'-Triphosphate Cytidine-5'-monophosphate

Application Analytes:

Adenosine Triphosphate
Cytidine Diphosphate

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