DEA (Diethanolamine)

CAS Number	111-42-2
Molecular Formula	C4H11NO2
Molecular Weight	105.137 g/mol
InChI Key	ZBCBWPMODOFKDW-UHFFFAOYSA-N
LogP	-1.44
Synonyms	Diethanolamine 2,2'-Azanediyldi(ethan-1-ol) Ethanol, 2,2'-iminobis- Ethanol, 2,2'-iminobis- 2,2'-Iminobisethanol 2-(2-Hydroxy-ethylamino)-ethanol 4-04-00-01514 Beilstein Registry Number 2,2'-Dihydroxydiethylamine 2,2'-Iminobis[ethanol] 2,2'-Iminodi-1-ethanol 2,2'-iminodietanol 2,2'-Iminodiethanol 2,2-Iminodiethanol 2-[(2-Hydroxyethyl)amino]ethanol Bis(2-hydroxyethyl)amine Bis(hydroxyethyl)amine Dabco DEOA-LF DEAO-LF Di(2-hydroxyethyl)amine Di(?-hydroxyethyl)amine DIAETHANOLAMIN Diethanolamine 80 Diolamine Ethanol, 2',2'-iminobis- Ethanol, 2,2'-iminodi- Iminodiethanol N,N-Bis(2-hydroxyethyl)amine N,N-Di(2-hydroxyethyl)amine N,N-DIETHANOLAMINE N,N'-Iminodiethanol Niax DEOA-LF NSC 4959 BRN 0605315 Diethylamine, 2,2'-dihydroxy- N,N-Di(hydroxyethyl)amine EINECS 203-868-0 NCI-C55174 Di(beta-hydroxyethyl)amine UNII-AZE05TDV2V FDA Registry Number 2,2'-Iminobis 2,2'Iminobisethanol 2-(2-hydroxyethylamino)ethanol 2-[(2-hydroxyethyl)amino]ethan-1-ol Aliphatic amine Bis(2-hydroxyethyl)tallow amine oxide Bis-2-hydroxyethylamine DEA Di(beta-hydroxyethyl)amine Diethanolamin Diethylolamine Dihydroxyethyl tallowamine oxide H2dea N,N-di(hydroxyethyl)amine bis-(2-hydroxy-ethyl)-amine

Applications:

HPLC Separation of Glyphosate Production Intermediates

Glyphosate is a broad spectrum herbicide used to kill weeds. It is the most used herbicide. Glyphosate is an aminophosphonic analogue of the natural amino acid glycine. Glyphosate and its intermediates are very polar ionic compounds derived from glycine. Neither of intermediates can be retained on traditional reversed-phase columns. Two methods for glyphosate intermediates were developed on Primesep B, Primesep B2 and Primesep 100 columns.

Condition
Column	Primesep B, Primesep B2, Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase	MeCN/H2O
Buffer	TFA, H2SO4
Flow Rate	1.0 ml/min
Detection	ELSD

Description
Class of Compounds	Insecticide, Herbicide, Fungicide, Hydrophobic, Ionizable
Analyzing Compounds	Glyphosate, PMIDAA, IDA

DEA (Diethanolamine)
Diethanolamine
Glyphosate
IDA (Iminodiacetic acid)
Iminodiacetic Acid
PMIDA (Phosphonomethyliminodiacetic acid)
Phosphonomethyliminodiacetic Acid

HPLC Separation of Glyphosate Reaction Intermediates and Impurities

Glyphosate and intermediates/impurities of production are separated on an Obelisc N HILIC/ion-exchange column by a combination of HILIC and ion-exchange mechanism. Method can be used in analysis of glyphosate, iminodiacetic acid, (N-phosphonomethyl)-imminodiacetic acid, diethanolamine and related impurities in reaction mixtures, waste and ground waters. Detection techniques are LC/MS, ELSD, CAD and UV.

Condition
Column	Obelisc N, 4.6x150 mm, 5 µm, 100A
Mobile Phase	MeCN/H2O
Buffer	Ammonium Formate
Flow Rate	1.0 ml/min
Detection	ELSD

Description
Class of Compounds	Herbicide, Hydrophilic, Ionizable
Analyzing Compounds	Glyphosate, IDA, PMIDA, DEA

DEA (Diethanolamine)
Glyphosate
IDA (Iminodiacetic acid)
PMIDA (Phosphonomethyliminodiacetic acid)