Deoxyadenosine

CAS Number 40627-14-3
Molecular Formula C10H13N5O3
Molecular Weight 251.246 g/mol
InChI Key OLXZPDWKRNYJJZ-RRKCRQDMSA-N
LogP -0.5
Synonyms
  • 2'-deoxyadenosine
  • deoxyadenosine
  • 2-Deoxyadenosine
  • (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • Adenyldeoxyriboside
  • Adenine deoxyribonucleoside
  • Adenine deoxyribose
  • Desoxyadenosine
  • CCRIS 1782
  • UNII-P582C98ULC
  • 2'-dA
  • Adenine deoxyriboside
  • Adenine deoxy nucleoside
  • CHEBI:17256
  • 2'-deoxy-d-adenosine
  • AI3-52383
  • ADENOSINE, 2'-DEOXY-
  • (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  • EINECS 213-488-7

Applications:


Separation of Deoxyribo Nucleic Acid


Primesep 200 separates with baseline resolution the nucleosides (deoxyuridine, deoxyguanosine, deoxycytidine, deoxyadenozine) by a combination of cation exchange and reversed phase. These compounds are not retained on a traditional C18 column. Primesep 200 has an embedded anionic functional group which helps retain polar compounds by polar and ion-exchange mechanisms. Excellent peak shape results with a mass spec compatible mobile phase of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with UV detection at 270 nm.

Application Analytes:


Deoxyadenosine
Deoxycytidine
Deoxyuridine

HPLC Separation of Nucleobases (2)

Nucleosides consisting of deoxyribose and a nucleobase cannot be separated on a common C18 column. By using a Primesep 200 mixed-mode column with a cation-exchange mechanism, nucleosides: deoxyuridine, deoxyguanosine, deoxycytidine and deoxyadenosine, can be baseline separated in a short time using an isocratic method with a simple mobile phase of water, acetonitrile (MeCN, ACN) and TFA as buffer. UV detection at 270nm. 

Application Analytes:

Deoxyadenosine
Deoxycytidine
Deoxyuridine

HPLC Separation of Nucleosides and Deoxynucleosides

Th



Application Analytes:


Adenosine
Cytidine
Deoxyadenosine
Deoxycytidine
Guanosine
Thymidine
Uridine