Deoxyuridine

CAS Number 951-78-0
Molecular Formula C9H12N2O5
Molecular Weight 228.204 g/mol
InChI Key MXHRCPNRJAMMIM-SHYZEUOFSA-N
LogP -1.6
Synonyms
  • 2'-DEOXYURIDINE
  • deoxyuridine
  • 951-78-0
  • Uracil deoxyriboside
  • 2-Deoxyuridine
  • 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • Deoxyribose uracil
  • Uridine, 2'-deoxy-
  • 2'-Desoxyuridine
  • UNII-W78I7AY22C
  • CCRIS 2832
  • dURD
  • EINECS 213-455-7
  • BRN 0024433
  • 2 -Deoxyuridine
  • CHEBI:16450
  • 1-(2-Deoxy-beta-D-erythro-pentofuranoxyl)uracil
  • MFCD00006527
  • 1-(2-Deoxy-beta-D-ribofuranosyl)uracil
  • AK-54658

Applications:


Separation of Deoxyribo Nucleic Acid


Primesep 200 separates with baseline resolution the nucleosides (deoxyuridine, deoxyguanosine, deoxycytidine, deoxyadenozine) by a combination of cation exchange and reversed phase. These compounds are not retained on a traditional C18 column. Primesep 200 has an embedded anionic functional group which helps retain polar compounds by polar and ion-exchange mechanisms. Excellent peak shape results with a mass spec compatible mobile phase of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with UV detection at 270 nm.

Application Analytes:


Deoxyadenosine
Deoxycytidine
Deoxyuridine

HPLC Separation of Nucleobases (2)

Nucleosides consisting of deoxyribose and a nucleobase cannot be separated on a common C18 column. By using a Primesep 200 mixed-mode column with a cation-exchange mechanism, nucleosides: deoxyuridine, deoxyguanosine, deoxycytidine and deoxyadenosine, can be baseline separated in a short time using an isocratic method with a simple mobile phase of water, acetonitrile (MeCN, ACN) and TFA as buffer. UV detection at 270nm. 

Application Analytes:

Deoxyadenosine
Deoxycytidine
Deoxyuridine