Heparin

CAS Number 9005-49-6
Molecular Formula C26H42N2O37S5
Molecular Weight 1134.899 g/mol
InChI Key HTTJABKRGRZYRN-UHFFFAOYSA-N
LogP -10.8
Synonyms
  • heparin
  • enoxaparin
  • Clexane
  • Lovenox
  • LMWH
  • Ardeparin
  • Nadroparin
  • Tinzaparin
  • Low molecular weight heparin
  • Lovenox HP
  • 9005-49-6
  • SEMULOPARIN
  • PK-10169
  • Lipo-hepin
  • 2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
  • Enoxaparine
  • 6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
  • Low-Molecular-Weight Heparin
  • Normiflo
  • Heparin, Low Molecular Weight

Applications:


HPLC Separation of Heparines and Pentosan


Heparin and pentosan are highly-sulfated glucosaminoglucan, widely used in pharmaceutical industry. Both molecules carry a high negative density attributed to multiple sulfate groups. Due to a very polar and polymeric nature of these compounds, separating and quantifying them is a very difficult task. Heparin and its salt, along with pentosan, are separated on a Primesep N column in HILIC/anion-exclusion mode. Method can be used for quantitation of heparin and pentosan in biofluids and formulations. Elution is monitored by ELSD, CAD or LC/MS.



Application Analytes:

Heparin
Pentosan