Hydroquinidine

CAS Number 1435-55-8
Molecular Formula C20H26N2O2
Molecular Weight 326.440 g/mol
InChI Key LJOQGZACKSYWCH-UHFFFAOYSA-N
LogP 3.15
Synonyms
  • Hydroquinidine
  • (9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol
  • Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
  • 1435-55-8
  • Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
  • (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
  • (+)-Hydroquinidine
  • 10,11-Dihydroquinidine
  • Dihydroquinidine
  • Hydroconquinine
  • Hydrochinidin
  • hidroquinidina
  • 1415-00-5
  • 900786-91-6
  • 904813-09-8
  • 1089762-75-3
  • 1195456-48-4

Applications:


HPLC Separation of Quinine and Quinidine


Quinine and quinidine are diastreoisomers. Quinine is an alkaloid with fever-reducing analgetic and anti-inflammatory properties. Both compounds have the same structure, and the only difference is optical position at two centers. These two diastereoisomers were separated on achiral mixed-mode cation-exclusion Primesep B column. No separation is observed on traditional achiral reversed-phase column. This examples shows that even diastereoisomers can be separated on mixed-mode HPLC columns.



Application Analytes:

Hydroquinidine
Hydroquinone
Quinidine
Quinine