Ibandronic Acid

CAS Number 114084-78-5
Molecular Formula C9H23NO7P2
Molecular Weight 319.231 g/mol
LogP -0.362
  • Ibandronic acid
  • {1-Hydroxy-3-[methyl(pentyl)amino]propane-1,1-diyl}bis(phosphonic acid)
  • Phosphonic acid, [1-hydroxy-3-(methylpentylamino)propylidene]bis-
  • 114084-78-5
  • Ibandronate
  • Phosphonic acid, [1-hydroxy-3-(methylpentylamino)propylidene]bis-
  • UNII-UMD7G2653W
  • Acid ibandronico
  • Bondenza
  • Bonviva


HPLC Separation of Alendronic, Ibandronic, Etidronic Acids

Dronic acids are bisphosphonates that differ in their alkyl chains. Alendronate (Fosamax) marketed alone is used for osteoporosis and other bone diseases. It is also combined with Vitamin C (Fosavance). A short, 50 mm Primesep SB column separates alendronic, ibandronic, and etidronic acids. The HPLC separation uses a mobile phase of water, acetonitrile (MeCN, ACN), trifluoracetic acid (TFA) or ammonium formate and evaporative light scattering detection (ELSD) at 80°C.

Application Analytes:

Alendronic Acid
Etidronic Acid
Ibandronic Acid