L-Cysteine-S-Sulfate

CAS Number 1637-71-4
Molecular Formula C3H7NO5S2
Molecular Weight 201.210 g/mol
InChI Key NOKPBJYHPHHWAN-REOHCLBHSA-N
LogP -1.93
Synonyms
  • S-Sulphocysteine
  • 3-(Sulfosulfanyl)-L-alanine
  • L-Alanine, 3-(sulfothio)-
  • 1637-71-4
  • (2R)-2-amino-3-(sulfosulfanyl)propanoic acid
  • Alaninethiosulfuric acid
  • Cysteine-S-sulfate
  • Cysteine-S-sulfonate
  • Cysteine-S-sulphate
  • Cysteinyl-S-sulfonate
  • Cysteinyl-S-sulfonic acid
  • L-Cysteine S-sulphate
  • L-Cysteine hydrogen sulfate
  • L-Cysteine hydrogen sulfate (ester)
  • L-Cysteine hydrogen sulphate (ester)
  • L-Cysteine-S-sulfonate
  • L-Cysteinesulfonic acid
  • L-cysteine S-sulfate
  • S-Cysteinesulfonic acid
  • S-Sulfo-L-cysteine
  • S-Sulfocysteine
  • S-sulpho-L-cysteine

Applications:


HPLC Analysis of L-Cysteine-S-Sulfate on Primesep SB Column


Cysteine-S-sulfate (SSC) is produced by reaction of inorganic sulfite and cystine by a as-yet-unknown pathway, and is a very potent NMDA-receptor antagonist. Cysteine-S-sulfate is a very polar molecule with one basic group, one carboxylic group and one sulfate group. It is retained by Primesep SB column by combination of strong anion-exchange mechanism and weak reversed-phase mechanism. Compound can be monitored by LC/MS, ELSD, Corona or UV detectors. This HPLC method can be adopted as generic approach for analysis of acidic and hydrophobic drugs.



Application Analytes:

L-Cysteine-S-Sulfate