Lithium

CAS Number 7439-93-2
Molecular Formula Li
Molecular Weight 6.940 g/mol
InChI Key SIAPCJWMELPYOE-UHFFFAOYSA-N
Synonyms
  • Lithium
  • 7439-93-2
  • Lithium atom
  • Lithium element
  • UN 1415
  • EINECS 231-102-5
  • Lithium, metallic
  • UNII-9FN79X2M3F

Applications:


Reverse Elution Order in Separation of Alkali Cation
Primesep C separates a mixture of inorganic cations, potassium, sodium, and lithium, by a combination of cation exchange and complex formation. The peak order is reversed on the Primesep C column compared to the order normally obtained on columns that rely on cation exchange alone. The mobile phase mixture of water, acetonitrile (MeCN, ACN) and ammonium acetate is compatible with UV and evaporative light scattering detection (ELSD).

Condition

Column Primesep C, 4.6x50 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer AmAc
Flow Rate 1.0 ml/min
Detection ELSD 50C
 

Description

Class of Compounds Ions,  Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Sodium, Potassium,  Lithium, Chloride
 

Application Analytes:

Lithium
Potassium
Sodium

Complex of Cations on Primesep C is Effected by Organic Modifier
Primesep C separates a mixture of inorganic cations, potassium, sodium, and lithium, by a combination of cation exchange and complex formation. The peak order is reversed on the Primesep C column compared to the order normally obtained on columns that rely on cation exchange alone. In addition, the elution order can be rearranged by simply changing the organic modifier in the mobile phase from acetonitrile to methanol. The mobile phase mixture of water, acetonitrile (MeCN, ACN) or methanol (MeOH) and ammonium acetate is compatible with UV and evaporative light scattering detection (ELSD).

Condition

Column Primesep C, 4.6x50 mm, 5 µm, 100A
Mobile Phase MeOH, MeCN
Buffer AmAc pH 5.0
Flow Rate 1.0 ml/min
Detection ELSD 50C
 

Description

Class of Compounds Ions,  Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Sodium, Potassium,  Lithium, Chloride
 

Application Analytes:

Lithium
Potassium
Sodium

Separation of Metal Ions on Primesep 100 Column
Primesep 100 separates the monovalent cations, lithium, potassium, and sodium, and the divalent cations, zinc, manganese, and calcium. The cations are resolved by cation exchange. The mobile phase mixture of water, acetonitrile (MeCN, ACN) and trifluoroacetic acid (TFA) is evaporative light scattering detection (ELSD) compatible.

Condition

Column Primesep 100, 4.6x250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer TFA
Flow Rate 1.0 ml/min
Detection ELSD 50C
 

Description

Class of Compounds Ions,  Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Sodium, Phosphate, Magnesium, Calcium, Lithium, Zinc
 

Application Analytes:

Calcium
Chloride
Lithium
Magnesium
Potassium
Sodium
Zinc

Separation of Sodium, Potassium, Lithium, and Ammonium in Mixed-Mode HPLC
Inorganic cations and ammonia are usually analyzed by ion-exchange chromatography with a conductivity detector. Mixed-mode chromatography achieves the same goal with an ELSD detector. In addition to retaining ions, mixed-mode column can retain hydrophobic molecules also, making it possible to analyze a wide variety of ionic and non-ionic compounds in one run. In this method sodium, potassium, and lithium ions were separated along with ammonium ions on a Primesep 100 column. Detection technique is ELSD.

Condition

Column Primesep 100,  4.6x250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer TFA
Flow Rate 1.0 ml/min
Detection ELSD
 

Description

Class of Compounds Ions,  Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Sodium, Potassium,  Bromide, Ammonium


Application Analytes:

Ammonium Ion
Lithium
Potassium
Sodium