m-Cresol Purple

CAS Number 2303-01-7
Molecular Formula C21H18O5S
Molecular Weight 382.430 g/mol
LogP 3.44
  • Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[3-methyl-
  • 3,3-Bis(4-hydroxy-2-methylphenyl)-2,1lambda6-benzoxathiole-1,1(3H)-dione
  • 2303-01-7
  • Cresol purple
  • m-Cresolsulfonephthalein
  • EINECS 218-960-6
  • NSC 9607
  • m-Cresol Purple
  • UNII-85ODZ58K3D
  • 2877-89-6
  • 88492-48-2


HPLC Separation of m-Cresol Purple and Related Impurities

m-Cresol purple is indicator dye for spectrophotometric pH measurements. These measurements are widely used in oceanic CO2 research. Purity of the indicator is a critical issue in accurate determination and can cause uncertainty in pH measurement. Numerous attempts to purify m-cresol purple failed due to lack of separation or low loadability of HPLC columns. Primesep B2 method separates 4 major impurities from main compound. All impurities are well separated. m-Cresol Purple is hydrophobic and acidic in nature. Parent compound and impurities are retained based on reverse phase and anion-exchange mechanisms. Method can be used for high loadabiity preparative separation of acidic dyes.

Application Analytes:

m-Cresol Purple