m-Toluidine

CAS Number 108-44-1
Molecular Formula C6H4CH3NH2
Molecular Weight 107.156 g/mol
InChI Key JJYPMNFTHPTTDI-UHFFFAOYSA-N
LogP 1.4
Synonyms
  • m-Toluidine
  • 3-Methylaniline
  • 108-44-1
  • 3-Toluidine
  • Benzenamine, 3-methyl-
  • 3-AMINOTOLUENE
  • m-Methylaniline
  • m-Tolylamine
  • m-Toluidin
  • 3-Methylbenzenamine
  • m-Aminotoluene
  • m-Methylbenzenamine
  • 3-Amino-1-methylbenzene
  • 3-Aminophenylmethane
  • Aniline, 3-methyl-
  • 3-Aminotoluen
  • 1-Amino-3-methylbenzene
  • m-Toluidin [Czech]
  • m-Toluidyna [Polish]
  • 3-Aminotoluen [Czech]
  • 3-methylphenylamine

Applications:


HPLC Separation of Toluidine Isomers



Toluidine isomers are based on toluene and differ whether the primary amine is ortho, meta or para to the methyl group. A Primesep 200 column with an ammonium formate buffer or a Primesep 100 column with sodium phosphate baseline resolves the three regioisomers. The HPLC separation uses a mobile phase of water, acetonitrile (MeCN, ACN), ammonium formate, or sodium phosphate and ultraviolet (UV) detection at 250 nm.



Application Analytes:

Toluidines
m-Toluidine
o-Toluidine
p-Toluidine

HPLC Separation of Toluidine Isomers in Cation-Exchange Mode

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Isomers of toluidine were successfully retained and separated in cation-exchange mode on a Primesep S2 column. Primesep S2 column is a HILIC/cation-exchange column that can be operated in HILIC, cation-exchange, and anion-exclusion modes. Method and column are compatible with ELSD/LC/MS and UV and can be used for routine analysis of polar molecules.



Application Analytes:

Toluidines
m-Toluidine
o-Toluidine
p-Toluidine

Separation of Toluidine and Aminobiphenyl Isomers

Toluidine isomers and aminobyphenyl isomers are organic compounds each with a substituted amine group. Primesep 200 was used to separate these isomers. Primesep 200 separates isomers by interacting with polar molecules, retaining basic compounds, and additionally by reverse phase mechanism.



Application Analytes:

2-Aminobiphenyl
4-Aminobiphenyl
m-Toluidine
o-Toluidine
p-Toluidine