Niacinamide

Niacin Amide

CAS Number 98-92-0
Molecular Formula C6H6N2O
Molecular Weight 122.127 g/mol
InChI Key DFPAKSUCGFBDDF-UHFFFAOYSA-N
LogP -0.4
Synonyms
  • nicotinamide
  • niacinamide
  • 3-Pyridinecarboxamide
  • vitamin PP
  • Nicotinic acid amide
  • pyridine-3-carboxamide
  • Aminicotin
  • Amixicotyn
  • Papulex
  • Nicotylamide
  • Nikotinamid
  • Savacotyl
  • Benicot
  • Dipegyl
  • Endobion
  • Hansamid
  • Nicobion
  • Pelmine
  • Nicotinic amide
  • Delonin amide
  • Pelonin amide
  • Vi-Nicotyl
  • Austrovit PP
  • Inovitan PP
  • Nicosylamide
  • Nicotilamide
  • Nicotililamido
  • Amnicotin
  • Niacevit
  • Nicamina
  • Nicamindon
  • Nicofort
  • Nicomidol
  • Nicotamide
  • Nicovitina
  • Nicovitol
  • Nicozymin
  • Niocinamide
  • Niozymin
  • Nicasir
  • Nicogen
  • Nicota
  • Nicotol
  • Nicovit
  • Niko-tamin
  • 3-Carbamoylpyridine
  • Nicotine acid amide
  • Nandervit-N
  • Pyridine-3-carboxylic acid amide

Applications:

HPLC Analysis of Active Drug in a Formulation
HPLC method for separation of active ingredients of drug/supplemental composition was developed on an Obelisc R trimodal HPLC column. Compounds are retained by combination of reversed-phase, cation-exchange and anion-exchange mechanisms. Compounds are well separated, and method can be used for quantitation of pyridoxine, ascorbic acid, niacinamide, pantothenic acid, caffeine and riboflavin in a mixture or as separate compounds in various complex mixtures. Various detection techniques can be applied for quantitation (ELSD, UV, LC/MS, Corona). This HPLC method can be adopted as general approach for analysis of active drug components in various formulations.

Condition
Column Obelisc R , 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O  -5/95%
Buffer NaHPO4 pH 3.0 - 30 mM
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description
Class of Compounds Drug, Vitamin B₆, Hydrophobic, Ionizable
Analyzing Compounds Pyridoxine, Ascorbic acid, Niacinamide, Pantothenic acid, Caffeine, Riboflavin

Application Analytes:

Ascorbic Acid
Caffeine
Niacinamide
Pantothenic Acid
Pyridoxine
Riboflavin (Vitamin B2)