Polysorbate 20

CAS Number 9005-64-5
Molecular Formula C26H50O10
Molecular Weight 522.676 g/mol
InChI Key HMFKFHLTUCJZJO-UHFFFAOYSA-N
LogP 2.5
Synonyms
  • Tween 20
  • Polysorbate 20
  • POLYOXYETHYLENE SORBITAN MONOLAURATE
  • Polyoxyethylene (20) sorbitan monolaurate
  • Polysorbate (INN)
  • 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
  • 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate
  • Alkest TW 20
  • Polysorbate 20 (NF)
  • Polysorbate 40 (NF)
  • Polysorbate 60 (NF)
  • Tween(R) 20
  • tween (R) 20
  • Tween 20 (TN)
  • Tween 40 (TN)
  • Tween 60 (TN)
  • Polysorbate 20 100ml
  • Polysorbate 40 100ml
  • Polysorbate 60 100ml
  • AC1L9EF5
  • SCHEMBL118527
  • POE (6) sorbitol monolaurate
  • POE(20) sorbitan monolaurate
  • CHEMBL371631
  • Ethoxylated Sorbitan monolaurate
  • POE (20) sorbitan monolaurate
  • MFCD00165986
  • E432
  • Polyoxyethylene Sorbitan Monolaurate Kosher
  • FT-0645136
  • Polyoxyethylene Sorbitan Monolaurate 20 NF
  • POLY(OXYTHEYLENE)N-SORBITAN-MONOLAURATE
  • 2-[2-[3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate

Applications:


HPLC Retention of Polysorbate on Primesep D Column



Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Surfactants that are esters of plain (non-PEG-ylated) sorbitan with fatty acids are usually referred to by the name Span. It is often required to quantitate Polysorbate (Polysorbate/Tween 20, Polysorbate/Tween 40, Polysorbate 60/Tween 60 and Polysorbate 80) by HPLC in various formulations. Polysorbates exist in form of oligomers. All oligomers are separated on Primesep D HPLC column. One of the oligomers can be used in quantitating polysorbate in various drug and food formulations.



Application Analytes:

Polysorbate
Polysorbate 20
Polysorbate 80

HPLC Analysis of Polysorbate in Mixture with Amino Acids and Sugar


Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Surfactants that are esters of plain (non-PEG-ylated) sorbitan with fatty acids are usually referred to by the name Span. It is often required to quantitate Polysorbate (Polysorbate/Tween 20, Polysorbate/Tween 40, Polysorbate 60/Tween 60 and Polysorbate 80) by HPLC in various formulations. Polysorbates exist in form of oligomers.

Application Analytes:

Amino Acids
Glycine
Histidine
Polysorbate
Polysorbate 20
Polysorbate 80
Sucrose
Tween 20
Tween 80