Spiramycin

36

CAS Number 8025-81-8
Molecular Formula C43H74N2O14
Molecular Weight 843.065 g/mol
InChI Key ACTOXUHEUCPTEW-JMRHEKERSA-N
LogP 2.1
Synonyms
  • spiramycin
  • ST075006
  • 8025-81-8
  • Espiramicin
  • Provamycin
  • Sequamycin
  • Spiramycine
  • Spiramycinum
  • Rovamycin
  • Antibiotic 799
  • NSC-64393
  • RP 5337
  • Rovamycine
  • Prestwick_121
  • 5337 R.P.
  • Prestwick2_000745
  • Prestwick3_000745
  • D0F5OR
  • AC1O4WG0
  • Spiramycin antibiotic complex
  • I06-1973
  • Spiramycin, European Pharmacopoeia (EP) Reference Standard
  • Spiramycin from Streptomyces sp., VETRANAL(TM), analytical standard
  • Spiramycin, Pharmaceutical Secondary Standard; Certified Reference Material

Applications:

Separation of Antibiotics in Mixed-mode chromatography
  A complex mixture of sulphonamide, macrolide, tetracycline and fluoroquinolone antibiotics were separated in one run using mixed-mode chromatography with LC/MS -compatible conditions. All compounds are separated based on reversed-phase and/or ion-exchange mechanism. Method can be used for analysis of various classes of antibiotics and related impurities in different sample matrices (blood, urine, soil, waste water).  

Condition
Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 0-25%, 6 min, 25-70% 14 min
Buffer Gradient Formic Acid - 0.05%-0.3%, 10 min, 14 min hold
Flow Rate 1.0 ml/min
Detection UV, 270 nm
 

Description
Class of Compounds  Antibiotic, Drug, Hydrophobic, Ionizable
Analyzing Compounds Sulphanilamide, Sulphaguanidine, Oxytetracycline, Marbofloxacin, Sulphadiazine, Chlortetracycline, Nofloxacin, Spiramycin, Cefalonium, Tylosin, Josamycin, Sulphamethoxazole, Dapsone, Sulphaquinoxalline, Flumequine
 
Application Analytes:

Carboxymethylcysteine
Chlortetracycline
Dapsone
Flumequine
Josamycin
Marbofloxacin
Norfloxacin
Oxytetracycline
Spiramycin
Sulfamethoxazole
Sulfonamides
Sulphadiazine
Sulphaguanidine
Sulphanilamide
Sulphaquinoxaline
Tetracycline
Tylosin