Sulfonium Ions

Synonyms

    Applications:

    Separation of Sulphonium Ions in Polar Organic Mode

    October 4, 2005

    The separation of steroids on Primesep 100 demonstrates the versatility of Primesep columns in both polar organic and ion-exchange modes in the separation of sulfonium ions. The high organic mobile phase retains methane sulfonic acid by a polar organic mechanism and separates methoxydimethylsulphonium and trimethylsulfphonium cations by polar organic and cation exchange modes. The separation method uses a mobile phase mixture of water, acetonitrile (MeCN, ACN), and trifluoroacetic acid (TFA) with evaporative light scattering detection (ELSD).

    Condition

    Column Primesep 100, 4.6×250 mm, 5 µm, 100A
    Mobile Phase MeCN/H2O – 35/65%
    Buffer TFA
    Flow Rate 1.5 ml/min
    Detection ELSD

     

    Description

    Class of Compounds
    Acid, Hydrophilic, Ionizable
    Analyzing Compounds Sulphonium Ions, Methoxydimethylsulphonium, Trimethylsulfphonium

     

    Application Column

    Primesep 100

    The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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    Primesep C

    The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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    Application Analytes:
    Methanesulfonic Acid
    Methoxydimethylsulphonium
    Sulfonium Ions
    Trimethylsulfonium

    Application Detection:
    ELSD Detection
    SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.