Sulphaquinoxaline

Sulfaquinoxaline

CAS Number 59-40-5
Molecular Formula C14H12N4O2S
Molecular Weight 300.34 g/mol
InChI Key NHZLNPMOSADWGC-UHFFFAOYSA-N
Synonyms
  • Sulfaquinoxaline
  • 4-Amino-N-(quinoxalin-2-yl)benzene-1-sulfonamide
  • Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-
  • 2-p-Aminobenzenesulfonamidoquinoxaline
  • 2-p-Aminobenzenesulphonamidoquinoxaline
  • 4-Amino-N-2-quinoxalinylbenzenesulfonamide
  • Avicocid
  • BRN 0290026
  • Caswell No. 721
  • Compound 3-120
  • EINECS 200-423-2
  • EPA Pesticide Chemical Code 077901
  • Italquina
  • Kokozigal
  • NSC 41805
  • N-(2-Quinoxalinyl)sulfanilamide
  • N'-2-Quinoxalylsulfanilamide
  • Sulfabenzpyrazine
  • Sulfacox
  • Sulfaline
  • 2-Sulfanilamidobenzopyrazine
  • 2-Sulfanilamidoquinoxaline
  • 2-(p-Sulfanilamido)quinoxaline
  • Sulphaquinoxaline
  • Sulquin
  • N(sup 1)-(2-Quinoxalinyl)sulfanilamide
  • Ursokoxaline
  • Sulfaquinoxalina
  • Sulfaquinoxalinum
  • UNII-WNW8115TM9 FDA Registry Number
  • Sul-q-nox

Applications:

HPLC Separation of Antibiotics
HPLC.cloud View on hplc.cloud Antibiotics are widely used for treatment and prevention of bacterial infections.  Various antibiotics, particularly those with a sulfanilamide structure, were separated in HPLC using mixed-mode columns with varying strengths of ion-pairing groups.  Primesep 200 has weak acidic ion-exchange pairing groups while Newcrom A has strong acidic ion-exchange groups.  In addition, methanol can be used in the mobile phase on Newcrom A column.  The antibiotics were resolved on both columns with a gradient mobile phase consisting of acetonitrile (ACN) or methanol (MeOH), water and sulfuric acid (H2SO4) buffer.  UV detection at 275nm.

Condition 1
Column Primesep 200, 4.6x100 mm, 5 µm, 100A
Mobile Phase MeCN Gradient
Buffer H2SO4 - 0.5%
Flow Rate 1.0 ml/min
Detection UV 275 nm

Condition 2
Column Newcrom A, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeOH Gradient
Buffer H2SO4 Gradient
Flow Rate  0.5 ml/min
Detection UV 275 nm
 

Description
Class of Compounds Drugs, Antibiotics
Analyzing Compounds Sulfanilamide, Sulfadiazine, Sulfaguanidine, Dapsone, Sulfaquinoxaline

Application Analytes:

Dapsone
Sulfadiazine
Sulfaguanidine
Sulfanilamide
Sulphaquinoxaline